# Effectiveness of platelet-rich fibrin (PRF) block graft in managing intra-bony defects: A case report

**Authors:** Surthi Senthi, Harini S, Saranya Mohan, Vijayalakshmi Rajaram, C. Burnice Nalinakumari, D. Shunmuga Prasanth, Jaideep Mahendra

PMC · DOI: 10.6026/973206300211817 · Bioinformation · 2025-07-31

## TL;DR

This case report shows that PRF block grafts can effectively treat intra-bony defects and improve periodontal health.

## Contribution

The study demonstrates PRF block grafts as a viable and effective alternative for periodontal regeneration.

## Key findings

- PRF block grafts led to significant clinical improvements in pocket depth reduction.
- Radiographic evidence showed bone fill and enhanced healing in treated intra-bony defects.

## Abstract

Periodontal disease is a multifactorial condition affecting tissues and supporting bone, potentially leading to tooth loss. Therefore,
it is of interest to remove inflammatory tissues and restore health, utilizing techniques like guided tissue regeneration, bone grafts,
and root surface bio-modifications. Platelet-rich fibrin (PRF) is a promising biomaterial due to its autologous nature and regenerative
potential. This case report evaluates PRF block grafts in managing intra-bony defects, assessing pocket depth reduction, attachment
level gain, and radiographic bone fill. The results showed significant clinical and radiographic improvements suggest PRF block grafts
as an effective modality for periodontal regeneration. Data shows PRF as a viable alternative to conventional grafting materials. PRF
may enhance healing and improve periodontal prognosis in treating intrabony defects.

## Linked entities

- **Diseases:** Periodontal disease (MONDO:0002635)

## Full-text entities

- **Diseases:** intra-bony defects (MESH:D018213), tooth loss (MESH:D016388), intrabony defects (MESH:D000013), inflammatory (MESH:D007249), Periodontal disease (MESH:D010510)

## Full text

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569914/full.md

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Source: https://tomesphere.com/paper/PMC12569914