# Evaluation of MODS and survival outcome in infectious diseases using SOFA and SAPS scores

**Authors:** Kush Narayan Ghanghoria, Jha R.K, Sachin Parmar

PMC · DOI: 10.6026/973206300212262 · Bioinformation · 2025-07-31

## TL;DR

This study compares two scoring systems to predict mortality in ICU patients with infectious diseases and finds one to be more accurate.

## Contribution

The study demonstrates that SOFA is more effective than SAPS in predicting mortality in ICU patients with infectious diseases.

## Key findings

- SOFA showed higher sensitivity and specificity in predicting mortality compared to SAPS.
- SOFA had a higher area under the curve (AUC) for mortality prediction.
- SOFA is a more reliable tool for assessing mortality risk in ICU patients with infectious diseases.

## Abstract

The predictive ability of the Simplified Acute Physiology Score (SAPS) and Sequential Organ Failure Assessment (SOFA) in forecasting
mortality in critically ill patients with infectious diseases leading to multiorgan dysfunction syndrome (MODS) is of interest. Hence, a
total of 60 patients were analyzed. Data shows that SOFA outperformed SAPS in predicting mortality, with higher sensitivity, specificity,
and area under the curve (AUC). Thus, SOFA is a more reliable tool for assessing mortality risk in ICU patients, improving clinical
decision-making.

## Full-text entities

- **Diseases:** Failure (MESH:D051437), infectious diseases (MESH:D003141), MODS (MESH:D009102), critically ill (MESH:D016638)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569893/full.md

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Source: https://tomesphere.com/paper/PMC12569893