# Salivary cotinine levels on periodontal conditions

**Authors:** Gayathri Muralidaran, Nagarathna D.V, Arpita Paul, Ramesh Babu

PMC · DOI: 10.6026/973206300211925 · Bioinformation · 2025-07-31

## TL;DR

This study compares the effects of beedi smoking and tobacco chewing on periodontal health and links them to salivary cotinine levels.

## Contribution

It shows that beedi smoking has a more significant negative impact on periodontal health than tobacco chewing.

## Key findings

- Beedi smoking has a statistically significant adverse effect on periodontal health compared to tobacco chewing.
- Salivary cotinine levels correlate with the number and duration of beedis smoked.
- Smoking beedis affects periodontium more than smokeless tobacco use.

## Abstract

The periodontal health among beedi smokers and tobacco chewers and its correlation to salivary cotinine levels is of interest. Hence,
60 tobacco-consuming male patients of which 30 patients were beedi smokers and 30 were smokeless tobacco users were enrolled in the
study. The gingival health and periodontal health were determined. Unstimulated saliva was collected and subjected to quantitative
Enzyme linked immunoassay (ELISA). There was a statistically significant effect on number and duration of beedi smoked than chewed
(p<0.001). Beedi smoking has more adverse effects on periodontium than tobacco chewing.

## Linked entities

- **Chemicals:** cotinine (PubChem CID 408)

## Full-text entities

- **Chemicals:** cotinine (MESH:D003367)
- **Species:** Homo sapiens (human, species) [taxon 9606], Nicotiana tabacum (American tobacco, species) [taxon 4097]

## Full text

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## References

37 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569892/full.md

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Source: https://tomesphere.com/paper/PMC12569892