# BODE index: A predictor of hospitalization and severity in chronic obstructive pulmonary disease patients

**Authors:** Dasari Ajay, Mini Bhatnagar, Namilla Chandra

PMC · DOI: 10.6026/973206300211831 · Bioinformation · 2025-07-31

## TL;DR

The BODE index helps predict hospitalization and severity in COPD patients, aligning with existing severity classifications.

## Contribution

The study confirms the BODE index's effectiveness in predicting COPD severity and hospitalization risk.

## Key findings

- The BODE index strongly correlates with GOLD grades and hospitalization frequency in COPD patients.
- A BODE index cut-off of >3 moderately predicts hospital admissions with 62.1% sensitivity and 62.6% specificity.
- The BODE index aligns closely with GOLD spirometry grades for COPD severity evaluation.

## Abstract

The BODE index (Body Mass Index, Airflow Obstruction, Dyspnoea, Exercise tolerance) as a predictor of hospitalization and disease
severity among Chronic obstructive lung disease (COPD) patients is of interest. Each patient's BODE index was calculated for 120 cases
classified by the GOLD criteria. A strong correlation was found between the BODE index, GOLD grades and hospitalization frequency. ROC
analysis confirmed that the BODE index significantly predicts severe COPD, with an AUC of 0.716. A cut-off value of >3 showed
moderate sensitivity (62.1%) and specificity (62.6%) for predicting hospital admissions. Thus, the BODE index is a reliable tool for
evaluating COPD severity and hospitalization risk, aligning closely with GOLD spirometry grades.

## Linked entities

- **Diseases:** Chronic obstructive pulmonary disease (MONDO:0005002), COPD (MONDO:0005002)

## Full-text entities

- **Diseases:** COPD (MESH:D029424)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569876/full.md

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Source: https://tomesphere.com/paper/PMC12569876