# Colposcopic evaluation of unhealthy cervix in gynecology patients: A prospective observational study

**Authors:** Archana Kori, Mohini Ahirwar, Jyoti Meravi, Manik Sirpurkar, Abhay Kumar

PMC · DOI: 10.6026/973206300212001 · Bioinformation · 2025-07-31

## TL;DR

This study compares colposcopy and Pap smear for detecting cervical abnormalities, finding colposcopy more sensitive but less specific.

## Contribution

The study provides new evidence on the effectiveness of combining colposcopy with cytology for early cervical lesion detection.

## Key findings

- Colposcopy had 83.3% sensitivity and 72.7% specificity for cervical lesions.
- Colposcopy-directed biopsy confirmed CIN in 21.3% of cases.
- Colposcopy and histopathology results correlated in 90.9% of cases.

## Abstract

Cervical cancer remains a major concern, especially in developing countries, highlighting the need for effective screening. In this
study of 150 women with clinically unhealthy cervix, colposcopy showed higher sensitivity (83.3%) but lower specificity (72.7%) compared
to Pap smear. Colposcopy-directed biopsy confirmed CIN in 21.3% of cases. The correlation between colposcopy and histopathology was
90.9%. Combining colposcopy with cytology enhances early detection of cervical lesions.

## Linked entities

- **Diseases:** cervical cancer (MONDO:0002974)

## Full-text entities

- **Diseases:** cervical lesions (MESH:D002575), Cervical cancer (MESH:D002583), unhealthy cervix (MESH:D002577)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569863/full.md

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Source: https://tomesphere.com/paper/PMC12569863