# Effect of perioperative fluid balance on the postoperative outcomes of patient after esophagectomy

**Authors:** Sofia Jaswal, Harsimran Singh Walia, Atin Goyal, Lalita Gouri Mitra, Nimish Singh, Vikram Singh

PMC · DOI: 10.6026/973206300211932 · Bioinformation · 2025-07-31

## TL;DR

This study examines how fluid balance during and after surgery affects recovery outcomes for patients who had esophagectomy.

## Contribution

The study identifies specific fluid balance metrics significantly associated with prolonged ICU stays after esophagectomy.

## Key findings

- Postoperative day 1 fluid balance is significantly linked to ICU stay duration (p-value 0.05).
- Cumulative fluid balance also shows a significant association with ICU stay (p-value 0.017).
- Patients with higher POD1 fluid balance had longer ICU stays (p-value 0.023).

## Abstract

The effect of perioperative fluid balance on the postoperative complications and outcomes among patients who underwent esophagectomy
surgery at a rural tertiary health care centre over 1 year is of interest. The effect of intraoperative and postoperative fluid balance
on the postoperative complications and length of ICU and hospital stay was studied. Postoperative day 1 (POD1) balance (p-value 0.05)
and cumulative fluid balance (p-value 0.017) were significantly associated with postoperative ICU stay. As the POD1 balance was
significantly associated with the ICU stay, we divided the patients into low- and high-balance groups based on the mean POD1 balance
(1484.74 mL), and ICU stay was found to be significantly longer in the high-balance group (p-value 0.023). POD1 balance and cumulative
fluid balance appear to be the most influential variables, exhibiting a substantial positive relationship with ICU stay.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569851/full.md

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Source: https://tomesphere.com/paper/PMC12569851