# Ipsa senectus morbus est? Approaching the unmet needs in geriatric depression: results from a national survey of medical experts

**Authors:** Umberto Albert, Carmine Tomasetti, Raffaele Antonelli Incalzi, Alessandro Cicolin, Alessandro Padovani, Michela Zanetti, Giuseppe Maina

PMC · DOI: 10.3389/fpsyt.2025.1583384 · Frontiers in Psychiatry · 2025-10-15

## TL;DR

This study explores challenges in diagnosing and treating geriatric depression through a survey of Italian geriatric physicians.

## Contribution

The paper identifies unmet needs in geriatric depression management based on expert physicians' insights.

## Key findings

- Geriatric depression is under-diagnosed and difficult to treat despite available antidepressants.
- Physicians report challenges in achieving remission in geriatric depression cases.
- The survey highlights the need for better strategies in managing late-life depression.

## Abstract

One of the main challenges of “real-world” management of depression is represented by geriatric depression, which is common and under-diagnosed. Depressive disorders represent the leading contributors to mental health-related global burden, and they are often diagnosed in the context of many comorbid disorders, such as cardiovascular disorders, Stroke, Parkinson’s Disease, Major Neurocognitive Disorders and Headache, thus worsening their outcomes. Depression, and above all geriatric depression, is a challenge for “real-world” clinicians, due to the low rates of remission despite the increasing number of antidepressant strategies currently available. Indeed, current antidepressant strategies often fail to achieve acceptable rates of remission. The challenge of diagnosis and treatment of geriatric depression in real world calls for the need of a deeper exploration of its management in clinical practice. This is the purpose of the present cross-sectional survey, aimed at evaluating the clinical approach to late-life depression in a sample of expert physicians working in geriatric settings in Italy.

Hereafter, we provide responses from 175 geriatrics-working physicians, which were recruited to participate in the survey through their membership in the Italian Society of Geriatrics and Gerontology (SIGG). They were invited to respond to a a 20-items questionnaire which was developed based both on literature review and on the a priori knowledge of the subject by the developing team, composed by seven expert physicians in the fields of Psychiatry, Neurology and Geriatrics

The survey was aimed at delving into the possible unmet needs in the management of geriatric depression according to the sample of physicians surveyed, thus trying to provide useful insights on geriatric depression care.

## Linked entities

- **Diseases:** depression (MONDO:0002050), Stroke (MONDO:0005098), Parkinson’s Disease (MONDO:0005180)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** Stroke (MESH:D020521), Headache (MESH:D006261), cardiovascular disorders (MESH:D002318), Depression (MESH:D003866), Neurocognitive Disorders (MESH:D019965), Ipsa senectus morbus (MESH:D017688), Parkinson's Disease (MESH:D010300)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12569647/full.md

## References

71 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569647/full.md

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Source: https://tomesphere.com/paper/PMC12569647