# ST-Elevation Myocardial Infarction (STEMI) in a Morphologically Pediatric Adult With Seckel Syndrome: A Report of a Rare Case

## TL;DR

A rare case of heart attack in a small adult with Seckel syndrome highlights challenges in treating such patients with standard medical tools.

## Contribution

First reported case of STEMI in a morphologically pediatric adult with Seckel syndrome.

## Key findings

- STEMI occurred in a 30-year-old male with Seckel syndrome weighing 11.5 kg.
- Standard treatments like thrombolysis and PCI were not feasible due to patient's medical history and small size.
- The case resulted in multiorgan failure and death despite intensive care.

## Abstract

Seckel syndrome is a rare genetic disorder characterized by severe growth retardation, microcephaly, and distinctive craniofacial features. Although cardiovascular anomalies have been sporadically reported, ST-elevation myocardial infarction (STEMI) has not been documented in this population.

To the best of our knowledge, we present the first case of anterior STEMI in a 30-year-old male with Seckel syndrome. The patient, weighing 11.5 kg, presented with acute chest and back pain and was diagnosed with anteroseptal STEMI. His complex medical history, including a coiled intracranial aneurysm, precluded thrombolysis, while his small body size and the absence of pediatric-compatible equipment rendered percutaneous coronary intervention (PCI) unfeasible. Despite maximal intensive care support, the patient developed multiorgan failure and died.

This case highlights the expanding cardiovascular manifestations of Seckel syndrome and the difficulties in applying standard STEMI management protocols to morphologically pediatric adults. The lack of specialized interventional tools and infrastructure in many regions further complicates care. This underscores the urgent need for multidisciplinary care models and specialized pediatric interventional cardiology services for syndromic adults.