# Role of Herbal Plants for Treatment of Coronary Artery Disease; A Review: Herbalism for Coronary Artery Disease

**Authors:** Leila Azizkhani, Sharareh Jahangiri, Seyedeh Mahya Dehestani, Hamid Hojati, Yahya Ebrahimi

PMC · DOI: 10.31661/gmj.v14i.3737 · Galen Medical Journal · 2025-02-21

## TL;DR

This review explores how herbal plants can help manage coronary artery disease and reduce stress, potentially improving heart health.

## Contribution

A comprehensive review of medicinal plants used in Iran for managing coronary artery disease and stress.

## Key findings

- Several medicinal plants like marjoram, lavender, and hawthorn are used for stress relief and CAD management.
- Combining herbal treatments with conventional therapies can enhance cardiovascular health and quality of life.
- Medicinal plants show low risk and broad therapeutic benefits for CAD patients.

## Abstract

Chronic stress is recognized as a significant risk factor for cardiovascular
disease and can worsen the condition of patients with coronary artery
disease (CAD). Traditional medicine is used to reduce stress and manage
various diseases, with a particular focus on cardiovascular health. This
study aimed to investigate the role of herbal supplements in the management
of coronary artery disease (CAD), focusing on their potential to alleviate
symptoms, enhance heart health, and reduce the risk of cardiovascular
complications in CAD patients, alongside the mechanisms of action underlying
their effects.

This comprehensive review evaluates the impact of medicinal plants on stress
and cardiovascular disease in research and studies with coronary artery
disease. Scientific articles were sourced from databases including PubMed,
Google Scholar, SID, and ScienceDirect, focusing on publications from 2000
to 2024. The selection criteria encompassed research and studies involving
various dosages of medicinal plants under different conditions. Only
articles in Persian and English were included, excluding those in other
languages. Data from the selected articles were extracted, specifically
focusing on medicinal plants effective as cardiac tonics within different
regions of Iran.

The findings indicate that various medicinal plants, including marjoram
(Origanum majorana), borage (Borago officinalis), lavender (Lavandula
angustifolia), valerian (Valeriana officinalis), hops (Humulus lupulus),
hawthorn (Crataegus spp.), rosemary (Rosmarinus officinalis), chamomile
(Matricaria chamomilla), dracocephalum (Dracocephalum moldavica), mint
(Mentha spp.), green tea (Camellia sinensis), and damask rose (Rosa
damascena), have been employed for stress relief and the management of CAD,
particularly in the context of mitigating cardiovascular disease risk
factors.

The combination of medicinal plants with other treatments can be an effective
strategy to reduce stress and enhance cardiovascular health in coronary
artery disease patients. Due to their low risk and broad therapeutic
benefits, these plants can improve patients’ quality of life when used
alongside conventional therapies.

## Linked entities

- **Diseases:** coronary artery disease (MONDO:0005010), cardiovascular disease (MONDO:0004995)
- **Species:** Origanum majorana (taxon 268884), Borago officinalis (taxon 13363), Lavandula angustifolia (taxon 39329), Valeriana officinalis (taxon 19953), Humulus lupulus (taxon 3486), Matricaria chamomilla (taxon 98504), Dracocephalum moldavica (taxon 39296), Camellia sinensis (taxon 4442)

## Full-text entities

- **Diseases:** CAD (MESH:D003324), cardiovascular complications (MESH:D002318)
- **Species:** Rosa x damascena (damask rose, species) [taxon 3765], Salvia rosmarinus (rosemary, species) [taxon 39367], Origanum majorana (sweet marjoram, species) [taxon 268884], Valeriana officinalis (common valerian, species) [taxon 19953], Borago officinalis (species) [taxon 13363], Humulus lupulus (common hop, species) [taxon 3486], Dracocephalum moldavica (species) [taxon 39296], Lavandula angustifolia (lavender, species) [taxon 39329], Crataegus (hawthorn, genus) [taxon 23159], Camellia sinensis (black tea, species) [taxon 4442], Matricaria chamomilla (species) [taxon 98504], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12569402/full.md

## References

35 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569402/full.md

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Source: https://tomesphere.com/paper/PMC12569402