# Case report: Adolescent breast hypertrophy with a tendency toward phyllodes tumor formation: first reported case in China

## TL;DR

A 14-year-old girl with rare adolescent breast hypertrophy underwent successful surgery, and her case showed a new link to potential phyllodes tumor formation.

## Contribution

This is the first reported case in China linking adolescent breast hypertrophy with potential phyllodes tumor formation.

## Key findings

- A 14-year-old patient had successful reduction mammoplasty for bilateral giant breast enlargement.
- Histopathological analysis revealed focal interstitial proliferation of myofibroblasts in the right breast.
- This case suggests a novel association between adolescent breast hypertrophy and potential phyllodes tumor development.

## Abstract

Adolescent breast hypertrophy is a rare and persistent condition that affects peripubertal females both physiologically and psychologically. We present a case of a 14-year-old patient with bilateral giant breast enlargement who underwent a successful reduction mammoplasty of 16.5% Body Weight. The right breast exhibited focal interstitial proliferation myofibroblasts, suggesting a potential risk for phyllodes tumor development. This finding represents a novel histopathological association, unreported in the literature and first documented in China.