# Blue spaces and incident dementia: Differences by geospatial and historical contexts

**Authors:** Kyle D. Moored, Michael R. Desjardins, Andrea L. Rosso, Gina S. Lovasi, Timothy M. Shields, Frank C. Curriero, Oscar L. Lopez, Michelle C. Carlson

PMC · DOI: 10.1002/alz.70850 · Alzheimer's & Dementia · 2025-10-28

## TL;DR

This study explores how proximity to water bodies relates to dementia risk, finding a higher risk in Pittsburgh linked to blue spaces.

## Contribution

The study identifies a specific association between blue spaces and vascular dementia in Pittsburgh, highlighting the importance of historical and spatial context.

## Key findings

- Greater blue space density in Pittsburgh was linked to higher mixed/vascular dementia risk.
- Associations were reduced after adjusting for neighborhood factors.
- Blue space density was not associated with dementia risk in the overall sample.

## Abstract

Blue spaces (i.e., water bodies) may benefit cognitive health depending on their uses and surrounding spatial context. We examined associations between blue spaces and incident dementia in the Cardiovascular Health Cognition Study, and specifically within Pittsburgh, given its industrial uses of blue spaces.

Participants were 2924 adults (Pittsburgh: n = 651) ≥65 years of age. Dementia was clinically adjudicated (1992–1999). Water density was measured using both 1 km radial buffers and U.S. Census tracts.

In Pittsburgh only, greater buffer‐level blue space predicted a higher risk of mixed/vascular dementia (highest vs lowest tertile: hazard ratio [HR] = 2.87, 95% confidence interval [CI]: 1.43–5.74), but not Alzheimer's disease (p > 0.05). This was attenuated adjusting for individual/neighborhood confounders (HR = 2.65, 95% CI: 0.99–7.07). Tract‐level associations were attenuated but significant after adjustment.

Blue space was related to vascular dementia risk after accounting for social context and using more personalized buffer‐level measures. Future studies should carefully consider spatial units and differentiate blue spaces by historical uses.

Examined associations between nearby blue spaces and incident dementia.Tested multiple spatial units (buffer, tract) and separately for the Pittsburgh site.Blue space density was not related to dementia risk in overall sample.Greater blue space density predicted a higher risk of dementia for the Pittsburgh site.Associations were attenuated after adjusting for neighborhood confounders.

Examined associations between nearby blue spaces and incident dementia.

Tested multiple spatial units (buffer, tract) and separately for the Pittsburgh site.

Blue space density was not related to dementia risk in overall sample.

Greater blue space density predicted a higher risk of dementia for the Pittsburgh site.

Associations were attenuated after adjusting for neighborhood confounders.

## Linked entities

- **Diseases:** dementia (MONDO:0001627), vascular dementia (MONDO:0004648), Alzheimer's disease (MONDO:0004975)

## Full-text entities

- **Diseases:** vascular dementia (MESH:D015140), Dementia (MESH:D003704), Alzheimer's disease (MESH:D000544), mixed (MESH:D060085)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12568378/full.md

## References

55 references — full list in the complete paper: https://tomesphere.com/paper/PMC12568378/full.md

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Source: https://tomesphere.com/paper/PMC12568378