# The Effective Way of Botulinum Toxin Injection to Reduce Bite Force: Preliminary Study

## TL;DR

This study shows that injecting botulinum toxin into multiple masticatory muscles reduces bite force more effectively and for a longer time than injecting fewer muscles.

## Contribution

The study demonstrates that multi-muscle botulinum toxin injections provide more prolonged bite force reduction compared to single or dual muscle injections.

## Key findings

- Injecting the medial pterygoid along with masseter and temporalis muscles leads to a more prolonged bite force reduction.
- Bite force reduction in the multi-muscle group lasted up to 4 months before recovery.
- Single and dual muscle injections showed transient bite force reduction that recovered within 1 month.

## Abstract

This study investigated bite force changes after botulinum toxin type A (BoNT-A) injection into different masticatory muscles. Thirty-five male participants were divided into three groups: masseter only (M), masseter and temporalis (MT), and masseter, temporalis, and medial pterygoid (MTP). Bite force was measured before and up to 6 months after injection with the Dental Prescale II system. Baseline values showed no significant group differences. Group M exhibited significant reduction at 1 and 2 weeks, with recovery within 1 month. Group MT showed a similar transient decrease, also recovering after 1 month. In contrast, Group MTP demonstrated a more pronounced and prolonged reduction, persisting up to 4 months before recovery. These results indicate that the extent and duration of BoNT-A effects depend on the number of muscles injected. Multi-muscle injections, including the medial pterygoid, provide more durable suppression. However, further research involving patient populations is needed to clarify whether multi-muscle injection strategies provide therapeutic benefits in clinical conditions such as temporomandibular disorders or oromandibular dystonia.