This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTED: Poma et al. In Vitro Modulation of P-Glycoprotein Activity by Euphorbia intisy Essential Oil on Acute Myeloid Leukemia Cell Line HL-60R. Pharmaceuticals 2021, 14, 111
Paola Poma, Manuela Labbozzetta, Aro Vonjy Ramarosandratana, Sergio Rosselli, Marco Tutone, Maurizio Sajeva, Monica Notarbartolo

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsBioactive Natural Diterpenoids Research · Biological Activity of Diterpenoids and Biflavonoids · Phytochemistry and Bioactivity Studies
The journal has retracted the article “In Vitro Modulation of P-Glycoprotein Activity by Euphorbia intisy Essential Oil on Acute Myeloid Leukemia Cell Line HL-60R” [1] cited above.
Following publication, concerns were brought to the attention of the Editorial Office regarding an image presented in this publication [1].
Adhering to our complaint procedure, an investigation was conducted by the Editorial Office and Editorial Board that confirmed indications of inappropriate editing within the Western blot presented in Figure 6. While the authors cooperated with the Editorial Office during the investigation, they were unable to satisfactorily explain the irregularities nor provide adequate raw material for the Editorial Board Evaluation. Consequently, the Editorial Board lost confidence in the reliability of the findings and decided to retract this publication [1], as per MDPI’s retraction policy (https://www.mdpi.com/ethics#_bookmark30 accessed on 26 August 2025).
This retraction was approved by the Editor-in-Chief of the journal Pharmaceuticals.
The authors did not agree to this retraction.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Poma P. Labbozzetta M. Ramarosandratana A.V. Rosselli S. Tutone M. Sajeva M. Notarbartolo M. RETRACTED: In Vitro Modulation of P-Glycoprotein Activity by Euphorbia intisy Essential Oil on Acute Myeloid Leukemia Cell Line HL-60R Pharmaceuticals 20211411110.3390/ph 1402011133572621 PMC 7922936 · doi ↗ · pubmed ↗
