# A 3-Year-Old Child With Incidental High-Dose Vitamin D Intoxication: A Case Report and Literature Review

**Authors:** Hossein Kasiri, Amir Hasan Farzaneh, Navid Khosravi

PMC · DOI: 10.1155/crie/6614996 · Case Reports in Endocrinology · 2025-10-21

## TL;DR

A 3-year-old child accidentally consumed a high dose of vitamin D but remained asymptomatic and recovered with proper medical care.

## Contribution

This case report adds to the literature on vitamin D toxicity in children and emphasizes the importance of public education on supplement safety.

## Key findings

- The child showed no symptoms after ingesting 800,000 IU of vitamin D3.
- Conservative treatment led to normalized lab results within 3 months.
- The case highlights the need for public awareness on safe supplement use in children.

## Abstract

Although rare, vitamin D toxicity is a serious condition that commonly results from excessive self-medication. Clinical manifestations range from asymptomatic hypercalcemia to severe, life-threatening complications. We present the case of a previously healthy 3-year-old child who accidentally ingested 800,000 IU of vitamin D3 (cholecalciferol) and remained asymptomatic. Management included intravenous hydration, oral prednisolone, and strict dietary calcium restriction, alongside regular monitoring of serum calcium and vitamin D levels. The patient was discharged after 11 days and showed normalized laboratory parameters during a 3-month follow-up. This case underscores the importance of early diagnosis, immediate cessation of vitamin D intake, and conservative medical management in preventing complications. It also highlights the critical need for public education regarding the safe use of dietary supplements, particularly in pediatric populations.

## Linked entities

- **Chemicals:** vitamin D3 (PubChem CID 5280795), cholecalciferol (PubChem CID 5280795), prednisolone (PubChem CID 5755)
- **Diseases:** hypercalcemia (MONDO:0001566)

## Full-text entities

- **Diseases:** hypercalcemia (MESH:D006934), toxicity (MESH:D064420)
- **Chemicals:** prednisolone (MESH:D011239), Vitamin D (MESH:D014807), cholecalciferol (MESH:D002762), calcium (MESH:D002118)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12566961/full.md

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Source: https://tomesphere.com/paper/PMC12566961