# Comparison of Metabolic Control, Dietary Habits, Activity, and Psychological Condition in Children and Adolescents Treated with Personal Insulin Pumps

**Authors:** Agnieszka Lejk, Karolina Myśliwiec, Jędrzej Chrzanowski, Jacek Burzyński, Arkadiusz Michalak, Malwina Musiał-Paździor, Marta Bandura, Jolanta Rutkowska-Kośmińska, Kinga Drzewińska, Aleksandra Grabowska, Mateusz Okonek, Marta Herstowska, Michał Hoffmann, Wojciech Fendler

PMC · DOI: 10.3390/nu17203304 · Nutrients · 2025-10-21

## TL;DR

This study compares how well insulin pumps with different features help manage diabetes in children and adolescents, focusing on blood sugar control, diet, activity, and mental health.

## Contribution

The study evaluates the impact of predictive low glucose suspend and advanced hybrid closed loop insulin pumps on metabolic and psychological outcomes in pediatric T1DM patients.

## Key findings

- Patients using predictive low glucose suspend and advanced hybrid closed loop systems showed significant differences in glucose metrics.
- Poor eating habits and irregular physical activity were common among participants.
- No significant differences in diabetes-specific quality of life were found between the two insulin pump groups.

## Abstract

Background: Type 1 diabetes mellitus (T1DM) is one of the most frequently occurring chronic metabolic conditions in the pediatric and adolescent population. That is why our aim in this study was to compare metabolic control, eating habits, activity, and mental health in patients using insulin pumps with predictive low glucose suspend (PLGS) and advanced hybrid closed loop (AHCL) systems. Methods: We selected 37 patients and collected clinical, continuous glucose monitoring (CGM), and question-naire data (food frequency questionnaire (FFQ-6), physical activity questionnaire for children (PAQ-C), pediatric quality of life inventory (PedsQL). Additionally, all pa-tients participated in culinary workshops, which included education on a low-glycemic-index diet. Results: We observed a significant difference between the PLGS and the AHCL groups for mean glucose, coefficient of variation, and Time in Range (≤54, 70–140, 70–180, ≥180, and ≥250 mg/dL). Patients with higher Time Below Range consumed juices or sugary drinks more frequently. All participants had incor-rect eating habits and engaged in irregular physical activity. Conclusions: We observed no significant differences in the diabetes-specific quality of life scores between the PLGS and AHCL groups.

## Linked entities

- **Diseases:** Type 1 diabetes mellitus (MONDO:0005147)

## Full-text entities

- **Genes:** INS (insulin) [NCBI Gene 3630] {aka IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10}
- **Diseases:** T1DM (MESH:D003922), AHCL (MESH:D005596), PLGS (MESH:D009800), diabetes (MESH:D003920)
- **Chemicals:** glucose (MESH:D005947), sugary drinks (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC12566938/full.md

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Source: https://tomesphere.com/paper/PMC12566938