# Management of Odontogenic Infections in Pregnant Patients: Case-Based Approach and Literature Review

**Authors:** Andrei Hramyka, Agata Wieczorkiewicz, Jakub Bargiel, Krzysztof Śliwiński, Krzysztof Gąsiorowski, Tomasz Marecik, Paweł Szczurowski, Grażyna Wyszyńska-Pawelec, Jan Zapała, Michał Gontarz

PMC · DOI: 10.3390/pathogens14101024 · Pathogens · 2025-10-09

## TL;DR

This study examines how odontogenic abscesses affect pregnant women differently, emphasizing the need for tailored treatment approaches during pregnancy.

## Contribution

The paper presents a case-based analysis and literature review on managing odontogenic infections in pregnant patients.

## Key findings

- Pregnant women showed more frequent severe complications from odontogenic abscesses, though not statistically significant.
- Antibiotic selection was based on gestational age, with beta-lactams being the preferred choice.
- Hospitalization was longer in pregnant patients due to maternal-fetal monitoring.

## Abstract

Background: Odontogenic abscesses may significantly affect maternal health during pregnancy. Aim: This study analyzes three cases of pregnant patients with odontogenic infections, comparing them to a control group of non-pregnant women, and reviews recent literature. Materials and Methods: Between January 2020 and April 2025, 3 pregnant and 70 non-pregnant women with odontogenic abscesses were treated. Clinical presentation, pathogens, therapy, and outcomes were compared. Results: Severe sequelae, such as rapid abscess spread and systemic inflammation, were more frequent in pregnant women, though not statistically significant (p = 0.068). Pregnant patients also tended toward prolonged intubation (p = 0.194) and targeted antibiotic use (p = 0.133). Antibiotic selection was based on gestational age, with beta-lactams preferred. Surgical interventions were more extensive, often involving multiple neck spaces. Hospitalization was longer (≥4 days in most cases) due to maternal–fetal monitoring. Conclusions: Odontogenic abscesses in pregnancy require individualized management and gestation-adjusted antibiotic therapy.

## Linked entities

- **Chemicals:** beta-lactams (PubChem CID 136721)

## Full-text entities

- **Diseases:** inflammation (MESH:D007249), Odontogenic Infections (MESH:D018126), Odontogenic abscesses (MESH:D000038)
- **Chemicals:** beta-lactams (MESH:D047090)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12566828/full.md

## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC12566828/full.md

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Source: https://tomesphere.com/paper/PMC12566828