# Tunable Electrokinetic Motion of Charged Nanoparticles in an Aqueous Solution Using Interdigitated Microelectrodes

**Authors:** Farshad Rezakhanloo, Yera Ussembayev, Mohammadreza Bahrami, Filip Beunis, Kevin Braeckmans, Ilia Goemaere, Deep Punj, Amin Ahmad, Louis Van der Meeren, Kristiaan Neyts

PMC · DOI: 10.3390/nano15201568 · Nanomaterials · 2025-10-15

## TL;DR

This paper introduces a simple and tunable method to control and separate nanoparticles using electric fields, enabling precise manipulation based on their electrokinetic behavior.

## Contribution

A novel, low-cost method for nanoparticle separation using interdigitated electrodes and AC electric fields, enabling control based on electrokinetic differences.

## Key findings

- Particles with small size differences but identical material composition can be separated using electrokinetic responses.
- Adjusting voltage frequency and amplitude allows selective particle accumulation in designated regions.
- The method is demonstrated to be effective for micro- and nanoparticles of the same material.

## Abstract

Electrokinetic phenomena offer promising tools for the manipulation of micro- and nanoparticles in liquid media. However, most existing techniques rely on complex configurations and are often limited to particle separation based on large size differences or distinct material properties. Here, we present a simple and tunable method for spatial control and separation of nanoparticles using interdigitated electrodes under AC electric fields. Our approach exploits subtle differences in the electroosmotic and dielectrophoretic responses of particles with small size variations but identical material compositions. By adjusting the frequency and amplitude of the applied voltage, particles can be selectively directed and accumulated at designated regions of the device, enabling precise control over their positioning and segregation. We demonstrate the effectiveness of our method using micro- and nanoparticles composed of the same material, achieving accurate spatial separation based solely on their electrokinetic behavior. This technique offers a low-cost, easily integrable platform for diverse applications, including cell manipulation, water purification, and targeted drug delivery.

## Full-text entities

- **Diseases:** injury to (MESH:D014947)
- **Chemicals:** AZ  726 MIF (-), Cl- (MESH:D002713), silanol (MESH:C082343), SiO2 (MESH:D012822), PS (MESH:D010758), ITO (MESH:C109984), HCl (MESH:D006851), Salt (MESH:D012492), H+ (MESH:D006859), Water (MESH:D014867), KCl (MESH:D011189), K+ (MESH:D011188), polystyrene (MESH:D011137), TMAH (MESH:C027917), OH- (MESH:C031356), FeCl3 (MESH:C024555)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12566736/full.md

## References

46 references — full list in the complete paper: https://tomesphere.com/paper/PMC12566736/full.md

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Source: https://tomesphere.com/paper/PMC12566736