# Spray-Dried Microcapsules of Lavandin (Lavandula × intermedia) Essential Oil: Formulation and Functional Properties

**Authors:** Jelena Bajac, Milena Terzić, Branislava Nikolovski, Lidija Petrović, Branimir Bajac, Gökhan Zengin, Ivana Mitrović

PMC · DOI: 10.3390/molecules30204098 · Molecules · 2025-10-15

## TL;DR

This study shows that spray drying can stabilize volatile lavandin essential oil, preserving its antimicrobial and cosmetic benefits for industrial use.

## Contribution

The study introduces an effective spray-drying method using Maltodextrin/Gum Arabic to encapsulate lavandin essential oil, enhancing its stability and functionality.

## Key findings

- Spray drying with Maltodextrin/Gum Arabic achieved high encapsulation efficiency and oil retention.
- Encapsulated lavandin retained antimicrobial and antifungal activity at low concentrations.
- Tyrosinase inhibition increased after encapsulation, suggesting cosmetic applications.

## Abstract

Lavandin essential oil (LEO) (Lavandula × intermedia) is a high-yielding aromatic product with broad bioactive potential, but its direct application is hindered by its volatility, rapid oxidation, and environmental sensitivity. In this study, the microencapsulation of LEO by spray drying using different wall materials was investigated: Maltodextrin (MD), Gum Arabic (GA), Whey Protein Concentrate (WPC), Inulin (IN), and Modified Starch (Hi-Cap). The resulting formulations exhibited encapsulation efficiencies (EEs) of 55.35–83.29%, oil retention (RE) of 49.07–76.65%, and yields of 41.39–71.47%. The MD/GA blend with Tween 80 performed best, as it offered high EE and RE, low residual moisture, fast reconstitution, and strong protection of the encapsulated oil against thermal and moisture stress. Gas chromatography–mass spectrometry (GC–MS) identified 38 volatile components, with linalyl acetate (30.38%) and linalool (24.65%) being the major components. Biological tests confirmed that the antimicrobial and antifungal activity of lavandin against some pathogens was maintained even when a much lower concentration of the oil (1–5%) was used in encapsulated form. Antioxidant activity decreased after encapsulation, while tyrosinase inhibition increased, indicating cosmetic potential. These results show that spray drying is an effective strategy for stabilizing LEO and expanding its applications in various industries.

## Linked entities

- **Chemicals:** linalyl acetate (PubChem CID 8294), linalool (PubChem CID 6549), Tween 80 (PubChem CID 443315)

## Full-text entities

- **Chemicals:** EE (-), Oil (MESH:D009821), linalool (MESH:C018584), GA (MESH:D006170), linalyl acetate (MESH:C074463), MD (MESH:C008315), IN (MESH:D007444), Tween 80 (MESH:D011136)
- **Species:** Lavandula x intermedia (species) [taxon 1196215]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12566211/full.md

## References

77 references — full list in the complete paper: https://tomesphere.com/paper/PMC12566211/full.md

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Source: https://tomesphere.com/paper/PMC12566211