# Purification, Structural Characteristics, Bioactive Properties, and Applications of Naematelia aurantialba Polysaccharides: A Comprehensive Review

**Authors:** Ri-Na Wu, Yun-Yang Zhu, Run-Hui Ma, Zhi-Jing Ni, Xiao-Juan Deng, Kiran Thakur, Zhao-Jun Wei

PMC · DOI: 10.3390/molecules30204073 · Molecules · 2025-10-13

## TL;DR

This paper reviews the properties and applications of polysaccharides from the golden ear fungus, highlighting their health benefits and potential in food, medicine, and cosmetics.

## Contribution

The paper provides a comprehensive review of the extraction, structure, bioactivity, and industrial applications of Naematelia aurantialba polysaccharides.

## Key findings

- N. aurantialba polysaccharides exhibit antioxidant, hypoglycemic, and anti-inflammatory effects.
- The review highlights the structural characteristics and functional mechanisms of NAPs.
- Current limitations and future research directions for NAPs are discussed.

## Abstract

Jin’er (Naematelia aurantialba), commonly known as golden ear, is a traditional edible fungus that has long been recognized for its medicinal and culinary properties in China. Recently, it has been registered as a new cosmetic ingredient, drawing significant attention across various fields, including medicine, food, and cosmetics, due to its array of nutritional and medicinal benefits. N. aurantialba is rich in bioactive compounds, such as polysaccharides, dietary fiber, polyphenols, and active peptides. Among these, N. aurantialba polysaccharides (NAPs) are the primary active components, exhibiting a range of biological properties, including antioxidant, hypoglycemic, immunomodulatory, intestinal flora modulatory, anti-tumor, and anti-inflammatory effects. This comprehensive review summarizes the latest advancements in the extraction, purification, structural characteristics, functional activity, and related functional mechanisms of NAPs, as well as their industrial applications. Additionally, it discusses the current limitations in NAPs research and explores its potential future research directions. This review aims to provide up-to-date information and valuable references for researchers and industry professionals interested in the potential application of NAPs in the fields of food, medicine, healthcare, and cosmetics.

## Linked entities

- **Species:** Naematelia aurantialba (taxon 371454)

## Full-text entities

- **Diseases:** inflammatory (MESH:D007249), tumor (MESH:D009369)
- **Chemicals:** polyphenols (MESH:D059808), N. aurantialba polysaccharides (-), polysaccharides (MESH:D011134)
- **Species:** Naematelia aurantialba (species) [taxon 371454]

## Full text

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## Figures

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## References

95 references — full list in the complete paper: https://tomesphere.com/paper/PMC12565800/full.md

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Source: https://tomesphere.com/paper/PMC12565800