# Personalized Nutrition in Pediatric Chronic Diseases

## TL;DR

This review explores how personalized nutrition, using advanced molecular data, can help manage chronic diseases in children, but highlights the need for practical and equitable solutions.

## Contribution

The paper synthesizes evidence on biomarkers and gene–environment interactions to advance personalized nutrition in pediatric chronic diseases.

## Key findings

- Personalized nutrition shows promise for managing pediatric chronic diseases through multi-OMICS insights.
- Biomarkers and gene–environment interactions are key for individualized dietary guidance.
- Challenges remain in translating molecular findings into accessible and cost-effective interventions.

## Abstract

This narrative review examines the application of personalized nutrition (PN) through multi-OMICS and trans-OMICS in pediatric populations, particularly in relation to chronic conditions such as obesity, type 2 diabetes, and celiac disease. We synthesize evidence to identify biomarkers and gene–environment interactions and translate molecular insights into individualized dietary guidance. Even though PN represents a promising strategy for optimizing child health, significant challenges remain in translating molecular findings into practical, cost-effective, and equitable interventions. We advocate integrating this knowledge into clinical practice and developing policies and standardized methodologies that ensure accessibility for all pediatric populations.