# Surgical Outcomes of Craniocervical Junction Fractures in Elderly Patients: A Retrospective Single-Center Series

**Authors:** Nicola Montemurro, Stefano Carnesecchi, Riccardo Morganti, Antonella De Carlo, Ardico Cocciaro

PMC · DOI: 10.3390/jpm15100485 · Journal of Personalized Medicine · 2025-10-10

## TL;DR

This study examines surgical outcomes for cervical spine fractures in elderly patients, finding acceptable results with some fusion and manageable complications.

## Contribution

The study provides insights into surgical fusion rates and outcomes for elderly patients with craniocervical junction fractures.

## Key findings

- 71.6% of elderly patients achieved good fusion (A-B grade) after surgery.
- Postoperative complications occurred in 12.25% of elderly patients.
- Most patients (97.3%) had ASIA E neurological status at admission.

## Abstract

Background: Fractures of the first and second cervical vertebrae are common in both young and elderly patients. Surgical management of C1–C2 fractures in elderly patients is controversial. The aim of this study is to report the rate of fusion in elderly patients who underwent surgery for C1 or C2 fractures. Methods: A retrospective review of all patients over the age of 65 years old who underwent surgical treatment for C1 or C2 fracture was reported. Visual analog scale (VAS) and neck disability index (NDI) were used to assess patients’ clinical outcome at 1 year follow-up. Cervical spine computer tomography (CT) scans were performed in all cases before surgery and at 1 year follow-up to evaluate the long-term postoperative rate of fusion, according to Lenke fusion grade. Results: From 2019 to 2023, 105 patients with cervical craniocervical junction (CCJ) fracture underwent surgical treatment in our Pisana University Hospital. Among all these, 74 patients (70.5%) were over 65 years old. The mean age of the study population was 76.9 years old (12.2% aged 65–70, 51.4% aged 70–79, and 36.5% over 80). According to the AO Spine Upper Cervical Injury Classification System, 6 (8.1%) patients presented a type II fracture and 68 (91.9%) patients presented a type III fracture. At admission, neurological examination resulted in American Spinal Injury Association (ASIA) E in 97.3% of cases. Over 60% of all patients underwent C1–C2 posterior fixation. Postoperative complications occurred in 12.25% of patients. According to the criteria described by Lenke, a good rate of fusion (A-B grade) was obtained in 71.6% of patients. Conclusions: In elderly patients with CCJ fractures, precision medicine can help identify those at higher risk for complications and guide personalized treatment strategies. Surgical treatment of CCJ fractures in elderly patients, although not always associated with bone fusion, can be performed with an acceptable incidence of mortality and morbidity, allowing rapid mobilization and return to pre-trauma levels of independence.

## Full-text entities

- **Diseases:** Junction Fractures (MESH:D020511), CCJ fractures (MESH:D020196), neck disability (MESH:D006258), trauma (MESH:D014947), Fractures (MESH:D050723), Cervical Injury (MESH:D002575), type III fracture (MESH:C536044), C1 or C2 fracture (OMIM:217000), Spinal Injury (MESH:D013124)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

68 references — full list in the complete paper: https://tomesphere.com/paper/PMC12565464/full.md

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Source: https://tomesphere.com/paper/PMC12565464