# The Role of Psychedelics in Contemporary Psychological and Interdisciplinary Inquiry

**Authors:** Kerem Kemal Soylemez, Emma Marie de Boo, Aysil Susuzlu, Joanne Lusher

PMC · DOI: 10.3390/jpm15100450 · Journal of Personalized Medicine · 2025-09-28

## TL;DR

This paper reviews how psychedelics are being studied for their mental health benefits and their impact across various scientific fields.

## Contribution

The paper emphasizes the need for ethical, multidisciplinary research on psychedelics to reshape mental health and cognitive science.

## Key findings

- Psychedelics show promise in treating mood disorders, PTSD, and addiction by enhancing neuroplasticity.
- They alter brain network dynamics and facilitate emotional processing and therapeutic breakthroughs.
- Interdisciplinary perspectives highlight their cultural, existential, and medical significance.

## Abstract

Psychedelic compounds are gaining renewed attention across disciplines for their profound psychological and neurobiological effects. Emerging research highlights their efficacy in treating mood disorders, PTSD, and addiction by enhancing neuroplasticity and disrupting maladaptive cognitive patterns. From a psychological standpoint, psychedelics facilitate introspection, emotional processing, and therapeutic breakthroughs. Neuroscientific findings reveal altered brain network dynamics, while anthropological and philosophical perspectives contextualize their cultural and existential significance. In medicine, they offer novel interventions for chronic pain and palliative care. The present review article underscores the need for rigorous, ethically grounded research to explore psychedelics’ potential in reshaping mental health paradigms and cognitive science from a multidisciplinary perspective.

## Linked entities

- **Diseases:** PTSD (MONDO:0005146)

## Full-text entities

- **Diseases:** addiction (MESH:D019966), mood disorders (MESH:D019964), PTSD (MESH:D013313), chronic pain (MESH:D059350)
- **Chemicals:** Psychedelic compounds (-)

## Full text

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## References

163 references — full list in the complete paper: https://tomesphere.com/paper/PMC12565330/full.md

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Source: https://tomesphere.com/paper/PMC12565330