# Can Improved Biosecurity Measures Reduce the Presence of the Most Common ESBL-Producing Enterobacteriaceae? A Study from Greek Pig Farms

## TL;DR

A study in Greek pig farms finds high rates of antibiotic-resistant bacteria and shows that better overall biosecurity measures can help reduce their presence.

## Contribution

The study demonstrates that comprehensive biosecurity measures are more effective than isolated controls in reducing ESBL-producing bacteria in swine farms.

## Key findings

- An 82% prevalence rate of ESBL-producing bacteria was found in Greek swine farms.
- Farms with low biosecurity scores were consistently vulnerable to ESBL contamination.
- Holistic biosecurity improvements are more effective than focusing on individual controls.

## Abstract

This study investigates the relationship between biosecurity implementation and the prevalence of ESBL-producing bacteria in Greek swine farms, revealing an alarming 82% prevalence rate, which is significantly higher than in other European nations. Our findings indicate that comprehensive biosecurity measures are more effective than focusing on priority controls alone. Notably, there was a lack of significant associations between farm size and individual biosecurity parameters, underscoring the importance of cumulative improvements across multiple measures. Moreover, we identified a critical threshold for biosecurity implementation: farms scoring less than a critical level were consistently vulnerable to ESBL contamination. Escherichia coli emerged as the dominant species among ESBL isolates, reflecting patterns seen globally. This suggests a need for targeted biosecurity strategies, as mixed species occurrences imply shared resistance pressures. Our results advocate for a paradigm shift in biosecurity practices, emphasizing holistic improvements across all measures rather than isolating specific controls. With current implementation levels averaging only 35% of recommended biosecurity practices, our findings highlight the urgent need for comprehensive interventions to mitigate antimicrobial resistance in the Greek swine industry.