# Patient Diagnosed Initially with Peripartum Cardiomyopathy, Later Rediagnosed with Peripartum Myocardial Infarction: A Case Report

**Authors:** Spas Kitov, Maria-Florance Kitova, Meri Hristamyan, Lyudmila Vladimirova-Kitova

PMC · DOI: 10.3390/life15101502 · Life · 2025-09-24

## TL;DR

A woman initially diagnosed with a heart condition during pregnancy was later found to have had a heart attack, highlighting the difficulty in distinguishing similar pregnancy-related heart issues.

## Contribution

This case report presents a rare instance where initial diagnosis of peripartum cardiomyopathy was later revised to peripartum myocardial infarction.

## Key findings

- Initial echocardiography showed normal heart function, but later imaging revealed a myocardial scar consistent with a prior heart attack.
- Multimodal imaging was crucial in reevaluating the diagnosis and understanding the progression of cardiac changes.
- The patient remained stable five years post-event despite initial heart complications.

## Abstract

Differentiating peripartum cardiomyopathy (PPCM) from pregnancy-associated myocardial infarction (PAMI) is challenging due to shared risk factors. We report a case of a 35-year-old woman who suffered a seizure and cardiac arrest in the final month of her second pregnancy. Echocardiography showed a normal left ventricular ejection fraction (LVEF). Three days later, she developed heart failure symptoms and a marked reduction in LVEF. After one month of treatment, LVEF nearly normalized, but regional wall motion abnormalities subsequently appeared, prompting coronary angiography, which showed normal coronary arteries. Thus, PPCM was diagnosed. One year later, cardiac magnetic resonance imaging, performed due to her wish for another pregnancy, showed a scar consistent with a previous transmural myocardial infarction. We interpret this as a case of PAMI. Despite medical contraindications, she became pregnant one year after the infarction and delivered via C-section. Five years post-event, there are no signs of heart failure. This case lies in the gray zone of pregnancy-related cardiac complications and highlights the importance of multimodality imaging for thorough structural and functional assessment.

## Linked entities

- **Diseases:** peripartum cardiomyopathy (MONDO:0018920), myocardial infarction (MONDO:0005068), heart failure (MONDO:0005252)

## Full-text entities

- **Diseases:** PPCM (MESH:D009202), PAMI (MESH:D020150), cardiac arrest (MESH:D006323), Peripartum Myocardial Infarction (MESH:D009203), heart failure (MESH:D006333), seizure (MESH:D012640), infarction (MESH:D007238), cardiac complications (MESH:D006331)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12565018/full.md

## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12565018/full.md

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Source: https://tomesphere.com/paper/PMC12565018