# Shifting Trends in Intensive Cardiovascular Care Unit Admission Patterns: Retrospective Insights and Prospective Implications

**Authors:** Ranel Loutati, Louay Taha, Mohammad Karmi, Noam Fink, Pierre Sabouret, Mamas A. Mamas, Ari Naimark, Ariella Tvito, Yonit Wiener-Well, Amjad Abu-Salman, Mony Shuvy, Ofer Merin, Michael Glikson, Elad Asher

PMC · DOI: 10.3390/diagnostics15202563 · Diagnostics · 2025-10-11

## TL;DR

This study examines changes in ICU admissions for heart conditions over five years, finding improved survival rates despite more complex cases.

## Contribution

The study provides new insights into evolving ICCU admission patterns and their impact on patient outcomes.

## Key findings

- Heart failure and arrhythmia admissions increased, while NSTEMI and pulmonary embolism cases decreased.
- Use of advanced procedures like microaxial pumps rose, while older methods declined.
- One-year mortality improved despite higher patient acuity in later years.

## Abstract

Background: Intensive Cardiovascular Care Units (ICCUs) are critical in managing high-acuity cardiovascular conditions, yet contemporary data on evolving admission patterns and their association with outcomes are limited. Methods: We conducted a retrospective cohort study of all patients admitted to a tertiary-care ICCU between July 2019 and December 2024. Patients were stratified by admission period: early (2019–2021) and late (2022–2024). Baseline characteristics, index diagnosis, interventions, complications, and mortality outcomes were compared. The primary endpoints were in-hospital and one-year mortality. Results: The study included 6266 patients (median age 69 years, 32% female). Of them, 3125 and 3141 patients were admitted in the early and late periods, respectively. Patients in the later period exhibited a higher burden of co-morbidities, including increased rates of atrial fibrillation, cognitive impairment, and dialysis (p < 0.05 for all). The pattern of index diagnoses shifted, showing an increase in heart failure (5.6% vs. 3.7%, p = 0.001) and malignant arrhythmia admissions (13.9% vs. 9.3%, p < 0.001), alongside a decline in cases of NSTEMI and pulmonary embolism. The use of urgent percutaneous coronary intervention, transcatheter valvular interventions, and microaxial pumps increased, whereas intra-aortic balloon pump usage declined. In-hospital mortality remained consistent between the periods at 2.7%. However, adjusted one-year mortality was significantly reduced in the later period (adjusted HR 0.84, 95% CI 0.71–0.98, p = 0.037). Conclusions: Over five years, ICCU admissions showed increasing complexity and evolving procedural trends. Despite higher acuity, adjusted one-year survival improved, highlighting care advances and the value of continuous data-driven ICCU optimization.

## Linked entities

- **Diseases:** atrial fibrillation (MONDO:0004981), heart failure (MONDO:0005252), pulmonary embolism (MONDO:0005279)

## Full-text entities

- **Diseases:** atrial fibrillation (MESH:D001281), malignant arrhythmia (MESH:D001145), cognitive impairment (MESH:D003072), heart failure (MESH:D006333), NSTEMI (MESH:D000072658), pulmonary embolism (MESH:D011655)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12564537/full.md

## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC12564537/full.md

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Source: https://tomesphere.com/paper/PMC12564537