# Management of Severe Pediatric Lower Lip Defect After Canine Bite with Polyhexamethylene Biguanide (PHMB), Full-Thickness Skin Graft (FTSG) and Compression Foam: A Case Report

**Authors:** Aba Lőrincz, Hermann Nudelman, Anna Gabriella Lamberti, Attila Vástyán, Enikő Molnár, Gábor Pavlovics, Gergő Józsa

PMC · DOI: 10.3390/children12101308 · Children · 2025-09-28

## TL;DR

A child with a severe lower-lip injury from a dog bite was successfully treated with a combination of PHMB, skin grafts, and compression foam, preserving function with minor cosmetic issues.

## Contribution

This case report presents a novel integrated approach for managing contaminated, extensive pediatric lower-lip defects.

## Key findings

- Primary closure was achieved with complete graft survival and no infection or reoperations.
- At 12 months, function was intact but modest aesthetic sequelae remained.
- The treatment preserved oral competence, speech, and lip mobility.

## Abstract

What are the main findings?
Primary closure was achieved in a large, lower-lip defect after a dog bite using an integrated approach (topical polyhexanide, FTSG secured with a polyurethane compression foam, oral antibiotics).Function remained intact; at 12 months, modest esthetic sequelae persisted (dyschromia, shallow border indentation, vellus hairs).

Primary closure was achieved in a large, lower-lip defect after a dog bite using an integrated approach (topical polyhexanide, FTSG secured with a polyurethane compression foam, oral antibiotics).

Function remained intact; at 12 months, modest esthetic sequelae persisted (dyschromia, shallow border indentation, vellus hairs).

What are the implications of the main findings?
This pediatric case shows that the combined intervention can yield stable function with moderate esthetic compromise in a contaminated, extensive lower-lip injury.Component-level effects are undetermined; comparative studies with validated outcomes are needed.

This pediatric case shows that the combined intervention can yield stable function with moderate esthetic compromise in a contaminated, extensive lower-lip injury.

Component-level effects are undetermined; comparative studies with validated outcomes are needed.

Introduction: Pediatric lower-lip dog bite injuries are challenging due to contamination, tissue loss, and the need to maintain function, appearance, and psychological well-being. This single case describes immediate definitive closure using sharp debridement with adjunct polyhexanide (PHMB), a full-thickness skin graft (FTSG), and a polyurethane (PU) compression foam bolster. Methods: A 10-year-old boy with a severe contaminated lower-lip defect underwent debridement and 0.04% PHMB irrigation. An upper-arm FTSG was inset and compressed with a suture-anchored PU dressing. Topical PHMB gel was used perioperatively and for seven days after bolster removal. Oral antibiotics were given for five days. The patient was discharged eight days after the injury with detailed wound care instructions. Results: Immediate definitive closure was achieved with complete graft survival and no infection, necrosis, unplanned early dressing changes, or reoperations. At 12 months, oral competence, speech, lip mobility, and contour were preserved. However, mild residual esthetic differences remained (dyschromia, shallow border indentation, vellus hairs on the graft). Conclusion: In this single descriptive case, primary closure of a lower-lip injury with the combined intervention was associated with an uncomplicated functional course and manageable esthetic trade-offs at 12 months. These observations are descriptive; comparative studies with standardized functional, esthetic, and psychosocial measures are needed.

## Linked entities

- **Chemicals:** polyhexamethylene biguanide (PubChem CID 57345804)

## Full-text entities

- **Diseases:** lower (MESH:D017116), Lower Lip Defect (MESH:D008047), necrosis (MESH:D009336), infection (MESH:D007239)
- **Chemicals:** PU (MESH:D011140), PHMB (MESH:C031233)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## References

41 references — full list in the complete paper: https://tomesphere.com/paper/PMC12564493/full.md

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Source: https://tomesphere.com/paper/PMC12564493