# Managing Cough in Pediatric Neuromuscular Disorders: Lung Function and Care Strategies

**Authors:** Simone Foti Randazzese, Grazia Fenu, Claudia Calogero, Enrico Lombardi, Sara Manti

PMC · DOI: 10.3390/children12101377 · Children · 2025-10-12

## TL;DR

This paper reviews how to manage cough in children with neuromuscular disorders to prevent respiratory issues and improve their quality of life.

## Contribution

The paper provides a comprehensive overview of cough physiology and management strategies specific to pediatric neuromuscular disorders.

## Key findings

- Impaired cough in children with NMDs increases the risk of respiratory complications.
- Multidisciplinary and early interventions are crucial for effective respiratory management.
- Airway clearance techniques and respiratory muscle training are key strategies for improving outcomes.

## Abstract

Children with neuromuscular disorders (NMDs) are at high risk for respiratory complications due to impaired cough and weakness of respiratory muscles. Effective cough is essential for airway clearance, infections’ prevention, and maintaining lung function. This narrative review explores the physiology of cough, the consequences of cough insufficiency, and methods for assessing respiratory function in pediatric NMDs. It discusses current care strategies including airway clearance techniques, respiratory muscle training, and preventive and supportive interventions. Emphasis is placed on multidisciplinary management and early intervention to improve outcomes and quality of life.

## Full-text entities

- **Diseases:** respiratory complications (MESH:D012140), infections (MESH:D007239), weakness of respiratory muscles (MESH:D018908), Cough (MESH:D003371), NMDs (MESH:D009468)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12564417/full.md

## References

84 references — full list in the complete paper: https://tomesphere.com/paper/PMC12564417/full.md

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Source: https://tomesphere.com/paper/PMC12564417