# Collaborative Funding Model to Improve Quality of Care for Metastatic Breast Cancer in Europe

**Authors:** Matti S. Aapro, Jacqueline Waldrop, Oriana Ciani, Amanda Drury, Theresa Wiseman, Marianna Masiero, Joanna Matuszewska, Shani Paluch-Shimon, Gabriella Pravettoni, Franziska Henze, Rachel Wuerstlein, Marzia Zambon, Sofía Simón Robleda, Pietro Presti, Nicola Fenderico

PMC · DOI: 10.3390/curroncol32100547 · Current Oncology · 2025-09-30

## TL;DR

A collaborative funding model in Europe aims to improve care for metastatic breast cancer patients by supporting independent projects focused on communication, education, and quality of life.

## Contribution

A novel collaborative funding framework was developed to support patient-centered projects for metastatic breast cancer care across Europe.

## Key findings

- Seven projects across five European countries were funded to address care gaps for metastatic breast cancer patients.
- The model involved stakeholders from academia, non-profits, healthcare, and pharma to create scalable solutions.
- An average of 171 healthcare professionals and 228,675 patients per project were impacted.

## Abstract

Breast cancer is the most commonly diagnosed cancer in women and remains a leading cause of cancer-related deaths. Although advances in early detection and treatment have improved outcomes, significant gaps in care persist, especially for those with metastatic breast cancer. To address these challenges, Pfizer and Sharing Progress in Cancer Care partnered to create a collaborative funding model that supports independent, patient-centered projects across Europe. Through a Request For Proposals-based three-step process, seven initiatives were funded to improve communication, education, therapy adherence, and quality of life for patients. This model brings together stakeholders from academia, non-profit organizations, healthcare professionals, and the pharmaceutical industry to support scalable, impactful solutions. The framework is adaptable to other diseases and regions, offering a practical approach to closing care gaps and informing future healthcare strategies.

Breast cancer (BC) is the most frequently diagnosed malignancy in women. Currently, BC is treated with a holistic and multidisciplinary approach from diagnostic, surgical, radio-oncological, and medical perspectives, and advances including in early detection and treatment methods have led to improved outcomes for patients in recent years. Yet, BC remains the second most common cause of cancer-related deaths among women and there is an array of gaps to achieve optimal care. To close gaps in cancer care, here we describe a collaborative Request For Proposals (RFP) framework supporting independent initiatives for metastatic breast cancer (MBC) patients and aiming at improving their quality of care. We set up a collaborative framework between Pfizer and Sharing Progress in Cancer Care (SPCC). Our model is based on an RFP system in which Pfizer and SPCC worked together ensuring the independence of the funded projects. We developed a three-step life cycle RFP. The collaborating framework of the project was based on an RFP with a USD 1.5 million available budget for funding independent grants made available from Pfizer and managed in terms of awareness, selection, and monitoring by SPCC. Our three-step model could be applicable and scalable to quality improvement (QI) initiatives that are devoted to tackling obstacles to reaching optimal care. Through this model, seven projects from five different European countries were supported. These projects covered a range of issues related to the experience of patients with MBC: investigator communication, information, and shared decision-making (SDM) practices across Europe; development, delivery, and evaluation of a scalable online educational program for nurses; assessment of disparities among different minority patient groups; development of solutions to improve compliance or adherence to therapy; an information technology (IT) solution to improve quality of life (QoL) of patients with MBC and an initiative to increase awareness and visibility of MBC patients. Overall, an average of 171 healthcare professionals (HCPs) per project and approximately 228,675 patients per project were impacted. We set up and describe a partnership model among different stakeholders within the healthcare ecosystem―academia, non-profit organizations, oncologists, and pharmaceutical companies―aiming at supporting independent projects to close gaps in the care of patients with MBC. By removing barriers at different layers, these projects contributed to the achievement of optimal care for patients with MBC.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** Cancer (MESH:D009369), BC (MESH:D001943)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

46 references — full list in the complete paper: https://tomesphere.com/paper/PMC12563530/full.md

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Source: https://tomesphere.com/paper/PMC12563530