# Vascular Access Devices for Stem Cell Transplantation: A Review of Catheter Types—A Crucial Step Towards the Enhancement of Patient Care

## TL;DR

This paper reviews different types of vascular access devices used in stem cell transplantation to improve patient care and outcomes.

## Contribution

The paper introduces a comprehensive review and selection algorithm for vascular access devices tailored to stem cell transplant types and patient needs.

## Key findings

- Peripheral access is preferred for RIC/NMA conditioning in stem cell transplants.
- CICC or PICC are recommended for MAC conditioning when peripheral access is not feasible.
- CVADs are essential for administering multiple therapies in stem cell recipients.

## Abstract

Stem cell transplantation necessitates versatile and diverse vascular access to facilitate intensive treatment. For autologous and allogeneic transplantation with reduced intensity conditioning (RIC) or non-myeloablative (NMA) conditioning, peripheral access is preferable. For allogeneic transplantation with myeloablative conditioning (MAC), consideration should be given to using a central venous catheter (CICC) or two peripherally inserted central catheters (PICC). CICC is the preferred device when the peripheral vasculature is not optimal for a PICC and when a complicated procedure is anticipated.

Central venous access devices (CVADs) play a pivotal role in managing stem cell recipients, providing reliable access for the administration of chemotherapy, blood products, progenitor infusion, parenteral nutrition, and other crucial treatments. This review critically evaluates the various types of CVADs commonly employed in transplant settings, examining their indications, complications, and best practices to enhance patient outcomes. Moreover, it emphasizes the significance of broadening the selection algorithm for vascular devices and incorporating patient expectations and comfort into routine clinical practice.