# Psychological and Physical Health Improvements After Coronary Bypass: A Longitudinal Study in Cardiovascular Rehabilitation

**Authors:** Anna Panzeri, Giovanni Bruno, Giorgio Bertolotti, Andrea Spoto, Daniela Corbellini, Andrea Brandonisio, Ornella Bettinardi

PMC · DOI: 10.3390/ejihpe15100203 · 2025-10-07

## TL;DR

This study shows that patients recovering from heart surgery experience significant improvements in both mental and physical health over time.

## Contribution

The study provides longitudinal evidence of psychological and physical health changes in CABG patients during rehabilitation.

## Key findings

- Depression and anxiety significantly decrease from admission to discharge.
- Physical health improves significantly during the 6-month follow-up period.
- Factors like age, sex, and ejection fraction influence health outcomes.

## Abstract

Background: Patients who undergo coronary artery bypass graft (CABG) surgery often experience both physical and psychological challenges in the post-acute phase and thus follow an integrated rehabilitation program. Objective: This study aimed to examine changes in anxiety, depression, physical health, and mental health from admission to discharge and during a follow-up period up to 6 months after discharge. Methods: This study investigated longitudinal trends in the psychological and physical health of 608 patients (aged 65.75 ± 9.03 years, 80% male) undergoing a multidisciplinary rehabilitation program following CABG surgery. Repeated measures linear mixed models were used. Results: Significant reductions in depression (b = −7.30, p < 0.001) and anxiety (b = −2.22, p < 0.001) from admission to discharge were predicted by factors such as age (dep: b = 0.08, p < 0.001), male sex (dep: b = −1.15, p < 0.001), psychological symptoms (depression predicted by anxiety: b = 0.24, p < 0.001; anxiety predicted by depression: b = 1.25, p < 0.001), and the absence of preexisting stress (dep: b = 0.68, p < 0.001; anx: b = 1.68, p < 0.018). During the follow-up period from 45 days to 6 months postdischarge, physical health significantly improved (b = 3.77, p < 0.001), as predicted by age (b = −0.14, p < 0.001), male sex (b = 3.22, p < 0.001), mental health (b = 0.14, p < 0.001), and ejection fraction >35% (b = 3.56, p < 0.05). Discussion: These findings highlight the importance of considering both physical and psychological factors when designing rehabilitation programs for postacute CABG patients.

## Full-text entities

- **Diseases:** anxiety (MESH:D001007), depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12562965/full.md

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Source: https://tomesphere.com/paper/PMC12562965