# Effects of Chewing Gum on Plaque Index: A 3-Dimensional Colorimetric Analysis

**Authors:** Luca Levrini, Piero Antonio Zecca, Virginia Bellora, Alessandro Deppieri, Stefano Saran, Nicola Giannotta, Andrea Carganico

PMC · DOI: 10.3390/dj13100474 · 2025-10-17

## TL;DR

This study shows that chewing gum with xylitol and fluoride can reduce dental plaque, and a new 3D colorimetric method accurately measures this effect.

## Contribution

The study introduces a novel 3D colorimetric analysis for measuring plaque reduction and validates it against traditional methods.

## Key findings

- Chewing gum reduced plaque scores by 14.8% in the experimental group.
- 3D colorimetric analysis strongly correlates with the Plaque Control Record.
- Natural saliva flow and pigment washout explain some plaque reduction in controls.

## Abstract

Background: This study aimed to evaluate the effectiveness of xylitol- and fluoride-containing chewing gum in reducing dental plaque using a novel 3D colorimetric analysis, and to compare results with the Plaque Control Record (PCR). Methods: An acute intervention study was conducted on 34 healthy adults (18–45 years). A plaque-disclosing solution was applied, and intraoral scans were taken before and after 15 min of gum mastication. Plaque was quantified with PCR and the Placca Read software, which analyzes colorimetric patterns of scanned images. Statistical analyses (Shapiro–Wilk test, paired t-test) were performed with Jamovi Software version 1.6.14. Results: A significant reduction in plaque scores was observed after chewing gum (p < 0.05). Mean reduction reached −14.8% in the experimental group versus −3.9% in controls, where natural saliva flow and pigment washout may explain the modest decline. The 3D analysis provided precise measurements across all dental surfaces and showed strong correlation with PCR, supporting its validity. Conclusions: These findings indicate that functional chewing gum can significantly reduce plaque accumulation even after a single use, and that 3D colorimetric analysis offers a reliable, comprehensive alternative to conventional indices.

## Linked entities

- **Chemicals:** xylitol (PubChem CID 6912), fluoride (PubChem CID 28179)

## Full-text entities

- **Diseases:** Plaque (MESH:D003773)
- **Chemicals:** xylitol (MESH:D014993), fluoride (MESH:D005459)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12562772/full.md

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Source: https://tomesphere.com/paper/PMC12562772