# Psychological Involvement in the Journey of a Patient with Localized Prostate Cancer—From Diagnosis to Treatment

**Authors:** Daniela Mihalcia Ailene, Gabriela Rahnea-Nita, Alexandru Nechifor, Liliana Florina Andronache, Mihaela Emilia Dumitru, Alexandru-Mihai Rebegea, Cristina Stefanescu, Roxana-Andreea Rahnea-Nita, Laura-Florentina Rebegea

PMC · DOI: 10.3390/diseases13100319 · 2025-10-01

## TL;DR

This paper explores how psychological factors influence treatment decisions and quality of life in elderly prostate cancer patients.

## Contribution

The study highlights the role of psychological flexibility and acceptance-based therapy in improving patient outcomes.

## Key findings

- Androgen deprivation therapy significantly impairs sexual function and quality of life in prostate cancer patients.
- Therapy through acceptance and commitment helps patients adjust to suffering and improve decision-making.
- Psychological support is essential in redefining life goals and enhancing treatment satisfaction.

## Abstract

Introduction: Prostate cancer is one of the most common neoplasia in men, and its clinical evolution is highly influenced by psycho-emotional factors, especially in elderly patients. Comorbidities, the perception of one’s identity and its impact on life quality become relevant variables in the therapeutic decision. Sexual dysfunction after treatment along with decreased libido, erectile dysfunction and ejaculatory dysfunction are significant problems in patients with prostate cancer. Case presentation: The present study presents the oncological evolution of an elderly patient with a dual diagnosis, prostate adenocarcinoma and lung squamous cell carcinoma, who faced a significant amount of medical and psychological challenges. Reluctance to hormone therapy was closely linked to the fear of sexual dysfunction, a very common reaction in elderly men concerned with maintaining autonomy and intimacy. The peculiarity of the case consists in the interaction between the evolution of the disease, the therapeutic decisions and the psychological impact on the patient. Discussion: Androgen deprivation therapy negatively influences multiple aspects of sexual function, significantly impairing the life quality of patients diagnosed with prostate cancer. In this context, therapy through acceptance and commitment is the appropriate one, its main purpose being to change the patient’s relationship with suffering—from struggle and rejection to active acceptance and value of the present. The intervention of the psychologist or the psychotherapist is essential in decision-making counseling, using coping techniques, the clarification of personal values and the involvement of the family in the decision-making process. Oncological psychology helps the patient redefine their life goals and priorities, not just to choose a treatment. Conclusions: Sexuality and psychological health are deeply affected by prostate cancer. Psychological flexibility and emotional support can mitigate this negative impact. The integration of therapy through acceptance and commitment in the rehabilitation after treatment increases effectiveness and patient satisfaction.

## Linked entities

- **Diseases:** prostate cancer (MONDO:0005159), prostate adenocarcinoma (MONDO:0005082), lung squamous cell carcinoma (MONDO:0005097)

## Full-text entities

- **Diseases:** lung squamous cell carcinoma (MESH:D002294), ejaculatory dysfunction (MESH:D006331), prostate adenocarcinoma (MESH:D000230), erectile dysfunction (MESH:D007172), Sexual dysfunction (MESH:D012735), Prostate Cancer (MESH:D011471), neoplasia (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12562625/full.md

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Source: https://tomesphere.com/paper/PMC12562625