# Venous Thromboembolism Occurrence in the Setting of Nexplanon Insertion with Multiple Risk Factors: A Case Report

**Authors:** Jennifer Chin, Sarah Taga

PMC · DOI: 10.3390/healthcare13202563 · 2025-10-11

## TL;DR

A postpartum patient with multiple risk factors developed a blood clot shortly after a Nexplanon implant, highlighting the need for vigilance in this high-risk period.

## Contribution

This case report adds to the understanding of VTE risks in postpartum patients with Nexplanon implants and multiple comorbidities.

## Key findings

- A postpartum patient with multiple risk factors developed VTE shortly after Nexplanon insertion.
- The patient recovered well after anticoagulation and Nexplanon removal.
- The case emphasizes the importance of considering VTE in postpartum patients with implants.

## Abstract

Postpartum patients experience a 60-fold increased risk for venous thromboembolism (VTE). We present a postpartum patient with severe pre-eclampsia, gestational diabetes, and a recent Cesarean delivery, who was diagnosed with a VTE hours after a Nexplanon insertion on venous duplex ultrasound. She was started on anticoagulation, had the Nexplanon removed, and recovered well. This case highlights the importance of clinical suspicion for VTE in the postpartum period, presenting a postpartum VTE coinciding with a subdermal implant placement.

## Linked entities

- **Diseases:** venous thromboembolism (MONDO:0005399), pre-eclampsia (MONDO:0005081), gestational diabetes (MONDO:0005406)

## Full-text entities

- **Diseases:** pre-eclampsia (MESH:D011225), gestational diabetes (MESH:D016640), VTE (MESH:D054556)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12562538