# Detecting Event-Related Spectral Perturbations in Right-Handed Sensorimotor Cortical Responses Using OPM-MEG

**Authors:** Hao Lu, Yong Li, Min Xiang, Yuyu Ma, Yang Gao, Xiaolin Ning

PMC · DOI: 10.3390/bioengineering12101022 · Bioengineering · 2025-09-25

## TL;DR

This study uses OPM-MEG to detect brain activity differences during right and left hand movements in right-handed people.

## Contribution

The study demonstrates OPM-MEG's ability to detect ERSP asymmetry in right-handed motor responses.

## Key findings

- OPM-MEG successfully measured event-related spectral perturbations during finger movements.
- Right-handed individuals showed significant ERSP differences between right and left hand movements.

## Abstract

The optically pumped magnetometer, OPM-MEG, has the potential to replace the traditional low-temperature superconducting quantum interference device, SQUID-MEG. Event-related spectral perturbations (ERSPs) can be used to examine the temporal- and frequency-domain characteristics of a signal. In this paper, a finger-tapping movement paradigm based on auditory cues is adopted, and OPM-MEG is used to measure the functional signals of the brain. The event-related spectral perturbation values of the right and left hands of right-handed people were calculated and compared. The results showed that there was a significant difference in the event-related spectral perturbations between the right and left hands of right-handed people. In summary, OPM-MEG has the ability to measure the event-related spectral perturbations of the brain during finger movements and verify the asymmetry of motor skills.

## Full-text entities

- **Diseases:** asymmetry (MESH:D005146)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12561971/full.md

## References

54 references — full list in the complete paper: https://tomesphere.com/paper/PMC12561971/full.md

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Source: https://tomesphere.com/paper/PMC12561971