# Dietary Supplementation with L-Serine Regulates Growth Performance, Carcass Traits, Meat Quality, and Intestinal Development in Broilers

**Authors:** Longlong Li, Mei Su, Lan Zhang, Junyi Luo, Ting Chen, Jiajie Sun, Yongliang Zhang, Qianyun Xi

PMC · DOI: 10.3390/ani15202965 · Animals : an Open Access Journal from MDPI · 2025-10-13

## TL;DR

Adding L-serine to broiler diets improves growth, meat quality, and intestinal development without harmful residues.

## Contribution

This study demonstrates L-serine's effectiveness as a safe feed additive for broiler production.

## Key findings

- L-serine supplementation increased body weight and daily weight gain in broilers.
- L-serine improved meat quality by reducing cooking loss and enhancing pH values.
- L-serine promoted intestinal development by increasing villus length and villus-to-crypt depth ratio.

## Abstract

This study evaluated the effects of adding L-serine to broiler diets. Appropriate supplementation significantly improved growth performance and feed conversion efficiency, reduced localized fat deposition, enhanced meat quality, and promoted intestinal morphological development. As a safe, residue-free feed additive, L-serine has the potential to increase broiler production efficiency and help ensure meat safety.

This study evaluated the effects of additional L-serine supplementation in diets on performance, carcass characteristics, meat quality and small intestine development in broilers. A total of 300 one-day-old unsexed Yellow-Feathered broilers were randomly divided into three groups with 10 replicates of 10 birds each. The broilers were fed basal diet (CON), basal diet + 0.085% L-Alanine (Isonitrogenous) and basal diet + 0.1% L-serine (0.1% Ser), respectively. The whole trial lasted for 42 d. The results showed that 0.1% L-serine supplementation in broiler diets could increase final body weight and average daily weight gain (p < 0.05) and had no significant effect on serum biochemical indexes (p > 0.05). Compared with the Isonitrogenous group, the 0.1% Ser group significantly reduced FCR (p < 0.05). Regarding meat quality, the 0.1% Ser group significantly increased by a*45 min and 24 h pH values, while it decreased by b*45 min values in both breast and leg muscles (p < 0.05) and reduced cooking loss in leg muscles (p < 0.05). L-serine effectively reduced localized fat deposition and promoted intestinal development. Morphometric analysis revealed significantly increased small intestinal villus length and villus length/crypt depth ratio in the 0.1% Ser group (p < 0.05). In conclusion, L-serine can be used as an effective supplement in broiler farming to improve its productivity.

## Linked entities

- **Chemicals:** L-serine (PubChem CID 5951), L-Alanine (PubChem CID 602)
- **Species:** Mus musculus (taxon 10090)

## Full-text entities

- **Chemicals:** L-Alanine (MESH:D000409), L-Serine (MESH:D012694)

## Full text

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## Figures

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## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC12560898/full.md

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Source: https://tomesphere.com/paper/PMC12560898