# Successful Coronary Artery Bypass Grafting in a Moyamoya Patient with Prior Encephaloduroarteriosynangiosis

**Authors:** Emrah Ereren, Şenay Canikli Adıgüzel, Vaner Köksal, Hüseyin Ağırbaş

PMC · DOI: 10.1093/icvts/ivaf246 · Interdisciplinary Cardiovascular and Thoracic Surgery · 2025-10-11

## TL;DR

A Moyamoya patient successfully underwent heart surgery after prior brain revascularization, highlighting the importance of staged procedures for neurological safety.

## Contribution

This case is one of the few documenting CABG in a Moyamoya patient after EDAS, emphasizing staged revascularization for neuroprotection.

## Key findings

- The patient had no neurological deficits after CABG, likely due to established collaterals from prior EDAS.
- Staged revascularization may improve outcomes in Moyamoya patients undergoing cardiac surgery.
- Intraoperative neuroprotection strategies were critical for successful surgery.

## Abstract

Background: Moyamoya disease is a progressive steno-occlusive vasculopathy affecting the intracranial internal carotid arteries and posing significant perioperative challenges during cardiac surgery.

Case presentatıon: We present a 54-year-old male with bilateral carotid artery occlusion who had previously undergone left-sided encephaloduroarteriosynangiosis (EDAS), with angiography confirming robust collateral formation from the superficial temporal to middle cerebral artery territory. Three years later, he developed severe multivessel coronary artery disease requiring surgical revascularization. Coronary artery bypass grafting (CABG) was performed using a pump-assisted beating-heart technique without aortic cross-clamping due to heavy ascending aortic calcification. Intraoperative neuroprotection included near-infrared spectroscopy monitoring, controlled PaCO2, hematocrit and blood pressure maintenance, mild hypothermia, and avoidance of vasoconstrictors.

Dıscussıon: The patient recovered uneventfully and was discharged without neurological deficits on postoperative day 10. Importantly, unlike previous Moyamoya cases undergoing CABG, this report describes one of the very few documented instances performed after EDAS.

Conclusıon: The presence of established indirect collaterals likely contributed to a favourable neurological outcome, underscoring that staged revascularization may confer significant neuroprotection and should be considered in preoperative planning for selected Moyamoya patients.

Moyamoya disease (MMD) is a chronic, progressive cerebrovascular disorder characterized by stenosis or occlusion of the intracranial internal carotid arteries and the development of fragile collateral networks at the brain’s base.

## Linked entities

- **Diseases:** Moyamoya disease (MONDO:0016820), MMD (MONDO:0018948), coronary artery disease (MONDO:0005010)

## Full-text entities

- **Diseases:** Moyamoya (MESH:D009072), steno-occlusive vasculopathy (MESH:D001157), hypothermia (MESH:D007035), coronary artery disease (MESH:D003324), carotid artery occlusion (MESH:D002340), ascending aortic calcification (MESH:D000094625), neurological deficits (MESH:D009461)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12560818/full.md

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Source: https://tomesphere.com/paper/PMC12560818