# Multilayer and crushed stent visualization using photon- counting detector computed tomography – a proof of concept

**Authors:** Eva Harmel, Simon Hellbrueck, Dario Bongiovanni, Philip Raake, Thomas Kroencke, Josua A. Decker, Daniel O. Bittner

PMC · DOI: 10.1038/s41598-025-25119-9 · 2025-10-27

## TL;DR

Ultra-high resolution photon-counting CT improves visualization of complex coronary stents in a phantom model.

## Contribution

Demonstrates UHR PCD-CT's potential for better stent imaging compared to standard resolution.

## Key findings

- UHR PCD-CT significantly improved in-stent lumen visibility compared to SR PCD-CT.
- UHR imaging showed better sharpness and less blooming artifact in complex stent scenarios.
- Improvements were most notable in small and crushed stents.

## Abstract

Photon‑counting detector CT (PCD‑CT) enables ultra‑high resolution (UHR, 0.2 mm) and may improve visualization of coronary stents compared with standard‑resolution (SR, 0.4 mm). In this ex- vivo study, we utilized a phantom heart model to simulate physiological attenuation and imitated the most common coronary bifurcation stenting techniques by creating multiple stent layers and stent- crush situations (single layer, crushed, two‑ and three‑layer). We compared UHR and SR PCD‑CT using Bv72 and Bv56 kernels. Objective endpoints were in‑stent lumen visibility, signal-to-noise ratio, and percentage change in stent attenuation; subjective image quality was rated on a 5‑point Likert scale (1 = excellent to 5 = non‑diagnostic). Depending on distribution, two‑sided t‑tests (mean ± SD) or Mann–Whitney U tests (median[IQR]) were applied, p‑values were Bonferroni‑corrected for multiple comparisons. In the pooled Crush cohort, UHR Bv72 improved in‑stent lumen visibility when compared with both, SR Bv72 (single-layer: 68.08 ± 4.30% vs. 79.03 ± 3.79%; crushed: 63.62 ± 4.97% vs. 74.73 ± 2.51%) and SR Bv56 (single-layer: 63.63 ± 4.47% vs. 79.03 ± 3.79%; crushed: 62.18 ± 3.55% vs. 74.73 ± 2.51%), all p < 0.01. The effect was even more pronounced in small stents (single‑layer 65.45 ± 1.91% (SR) vs. 77.11 ± 2.55% (UHR) and crushed 60.67 ± 2.67% vs. 74.00 ± 2.67%), both p < 0.01. Regarding subjective image quality, UHR was associated with better sharpness and less blooming, e.g., UHR Bv72 vs. SR Bv56 (multilayer: sharpness 1[0] vs. 2[0], blooming 1[0] vs. 2[0]; crush: sharpness 1[0] vs. 2[0], blooming 1[0] vs. 2[1]; all p ≤ 0.01) and UHR Bv72 vs. SR Bv72 (multilayer: sharpness 1[0] vs. 1[1], blooming 1[0] vs. 1[1]; crush: sharpness 1[0] vs. 1[1]; all p ≤ 0.05). These findings indicate that UHR PCD‑CT with Bv72 might enable assessment of complex stents in a phantom setting; even though clinical studies are warranted.

The online version contains supplementary material available at 10.1038/s41598-025-25119-9.

## Full-text entities

- **Diseases:** PCD (MESH:D007619)
- **Chemicals:** Bv72 (-)

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12559316/full.md

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Source: https://tomesphere.com/paper/PMC12559316