# Advances in diagnosis and treatment of lung cancer-associated obstructive pneumonia and lung abscess: synergistic strategies for infection control and antitumor therapy

**Authors:** Peijun Cao, Li Chen, Shaohua Xie, Bin Hu

PMC · DOI: 10.3389/fcimb.2025.1638997 · 2025-10-14

## TL;DR

This review discusses new strategies for managing lung cancer complications like pneumonia and abscesses by combining infection control and cancer treatment.

## Contribution

The paper highlights integrated strategies using targeted therapy, immunotherapy, and nanomedicine for managing lung cancer-related infections.

## Key findings

- Integrated clinical strategies balance infection control and antitumor therapy.
- Recent advances in nanomedicine show promise for treating pulmonary infections.
- Targeted therapy and immunotherapy are key in managing these complications.

## Abstract

Lung cancer-associated obstructive pneumonia and pulmonary abscess represent critical oncologic complications. Effective management hinges on dynamically balancing primary tumor control with secondary infection management. Recent major advances in targeted therapy, immunotherapy, and novel anti-infective technologies have driven a shift towards integrated, multidimensional clinical strategies.This review details diagnostic and therapeutic progress for these conditions, emphasizing the critical balance between controlling severe infections and managing antitumor therapy toxicities, alongside recent advances in nanomedicine for pulmonary infections.

## Linked entities

- **Diseases:** lung cancer (MONDO:0005138)

## Full-text entities

- **Diseases:** lung abscess (MESH:D008169), Lung cancer (MESH:D008175), pulmonary infections (MESH:D012141), obstructive pneumonia (MESH:D011014), infection (MESH:D007239), toxicities (MESH:D064420), oncologic (MESH:D000072716), tumor (MESH:D009369)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12558922/full.md

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Source: https://tomesphere.com/paper/PMC12558922