# Cross-union surgery for tibiofibular fractures in McCune-Albright syndrome: a case report and literature review

**Authors:** Hui Zhu, Yiwei Wang, Hanjie Zhuang, Pengfei Zheng, Yuping Tang

PMC · DOI: 10.3389/fped.2025.1663626 · 2025-10-14

## TL;DR

This paper reports a successful surgical treatment for a rare bone condition in a child with McCune-Albright syndrome.

## Contribution

The study introduces the cross-union surgical technique as a novel treatment for tibiofibular fracture nonunion in McCune-Albright syndrome.

## Key findings

- The cross-union technique using a Fassier-Duval rod and fixation resulted in stable bone connection without refracture.
- Radiographic scores indicated successful healing and functional improvement in the treated patient.

## Abstract

McCune-Albright syndrome (MAS) is a rare disease. MAS manifests in the skeletal system as Fibrous dysplasia (FD). In MAS patients, bone lesions often result in fractures under weight-bearing forces during childhood, and pseudarthrosis formation is highly likely after fractures. There is currently no ideal treatment for fractures in children with MAS. This case study presents the innovative application of the cross-union technique in treating a 14-year-old female MAS patient with a distal tibial and fibular fracture nonunion.

The patient had a history of conservative treatment with persistent symptoms, including an inability to bear weight and walk independently. A “cross-union” procedure was performed using a Fassier-Duval rod, locking plate, and K-wire fixation.

At the final follow-up 12 months postoperatively, x-rays revealed a stable “cross-union” bone connection at the distal ends of the tibia and fibula, with no occurrence of refracture or other complications. The Radiographic Union Score for Tibial Fractures (RUST) was 12, and the Olerud Molander Ankle Score was 60.

We successfully applied the “cross-union” technique to a MAS child with nonunion after a distal tibiofibular fracture. We look forward to further improvement and promotion of the “cross-union” technology in the future, bringing new hope for treating fractures in MAS/FD children.

## Linked entities

- **Diseases:** McCune-Albright syndrome (MONDO:0018919), Fibrous dysplasia (MONDO:0000845)

## Full-text entities

- **Diseases:** Tibial Fractures (MESH:D013978), fractures (MESH:D050723), bone lesions (MESH:D001847), and fibular fracture nonunion (MESH:D020427), nonunion (MESH:C538144), pseudarthrosis (MESH:D011542), MAS (MESH:D005359), FD (MESH:D005357)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12558728/full.md

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Source: https://tomesphere.com/paper/PMC12558728