# Humeral Shaft Fractures: Retrospective Cohort Comparing Operative Versus Nonoperative Management

**Authors:** Rodrigo A Beraldo, Caroline Izidorio Bernardes Silva, Isadora C Kobayashi, André A Picoli, Pedro M Rodrigues, Cassius A Ribeiro Filho, Ewerton Alexandre Galdeano, Renato Moraes

PMC · DOI: 10.7759/cureus.93332 · 2025-09-27

## TL;DR

This study compares surgical and non-surgical treatments for humeral shaft fractures and finds similar outcomes in function and pain after one year.

## Contribution

The study provides new comparative evidence on patient-reported outcomes for surgical versus non-surgical treatment of humeral shaft fractures.

## Key findings

- Surgical fixation and functional bracing result in comparable 12-month function and pain outcomes.
- Complications significantly affect functional recovery more than the initial treatment modality.
- Radial nerve neurapraxia was common but resolved within six months.

## Abstract

Introduction: Operative fixation and functional bracing are established options for humeral shaft fractures, yet comparative patient-reported outcomes at one year remain debated. We compared 12-month function and pain between treatments.

Methods: We included 74 patients (36 treated surgically with plate fixation and 38 with functional bracing). Retrospective analysis of a prospective cohort (Hospital de Caridade São Vicente de Paulo, a tertiary center in Jundiaí, São Paulo, Brazil, January 2020-December 2021), including adults with AO 12 A2/A3/B2 diaphyseal fractures treated with plate osteosynthesis or functional bracing. Primary outcomes were QuickDASH and Visual Analog Scale (VAS) pain at baseline and 12 months. ANCOVA adjusted for baseline and age; a sensitivity model included complications.

Results: QuickDASH improved from 72.4±9.5 to 23.2±19.7 (Δ−49.2±18.3) with bracing and from 76.0±9.4 to 28.6±25.5 (Δ−47.4±21.9) with surgery, with between-group Δ p = 0.701. VAS fell from 6.4±1.2 to 1.8±2.1 and from 6.6±1.5 to 2.4±2.8, with between-group Δ p = 0.497. Adjusted 12-month differences (surgery−conservative) were QuickDASH +3.76 (95% CI −5.91 to +13.43; p = 0.446) and VAS +0.65 (−0.35 to +1.66; p = 0.202). Complications occurred in 19/74 (25.6%; 12 surgical, seven conservative): radial nerve neurapraxia 12/74 (all resolved ≤6 months), delayed union in three surgical (grafted at four months), and nonunion in four conservative (converted to surgery). In adjusted models, any complication independently worsened 12-month QuickDASH (+23.15; 95% CI +2.78 to +43.53; p = 0.026) but not VAS (+0.02; p = 0.979).

Conclusions: At 12 months, surgical fixation and functional bracing yield comparable patient-reported function and pain. Treatment should be individualized, while prevention and prompt management of complications may have a greater impact on functional recovery than the initial modality.

## Full-text entities

- **Diseases:** diaphyseal fractures (MESH:D003966), nonunion (MESH:C538144), radial nerve neurapraxia (MESH:D020425), Humeral Shaft Fractures (MESH:D006810), pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12557454