Acquired Hemophilia A With Post‐Phlebotomy Compartment Syndrome

TL;DR

This paper reports a rare case of acquired hemophilia A presenting as post-phlebotomy compartment syndrome, highlighting the importance of early diagnosis.

Contribution

The paper presents an atypical clinical case linking acquired hemophilia A with post-phlebotomy complications.

Findings

Acquired hemophilia A can present with post-phlebotomy compartment syndrome.

Factor VIII inhibitors caused refractory bleeding in this case.

Early diagnosis requires high clinical suspicion for unusual presentations.

Abstract

Acquired hemophilia A should be considered in unexplained bleeding with isolated activated partial thromboplastin time prolongation, even if mild. This case demonstrates an atypical presentation—compartment syndrome post‐phlebotomy—with refractory bleeding due to factor VIII inhibitors. High clinical suspicion is essential for early diagnosis and management.

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