# Optimizing nursing care for neutropenic patients: a holistic perspective on education, support, and clinical management

**Authors:** Zhao-ning Xu, Li-ping Gao, Xin-kai Wang, Xiu-li Yu, Yue Cong, Peng-ju Wang

PMC · DOI: 10.3389/fmed.2025.1633708 · 2025-10-13

## TL;DR

This paper presents nursing strategies to improve care for neutropenic patients through education, support, and clinical management, aiming to reduce infection risks and improve outcomes.

## Contribution

The paper introduces a holistic framework combining clinical, educational, and psychosocial strategies for neutropenia management.

## Key findings

- Competency-based training and mHealth tools improved adherence by 42%.
- Telehealth and meaningful therapy reduced distress by 38–45%.
- Interdisciplinary pathways lowered complications by 25–30%.

## Abstract

Neutropenia, characterized by neutrophil counts below 1,500 cells/μL, increases infection risk and worsens treatment outcomes in oncology and immunocompromised patients. This paper outlines evidence-based nursing strategies in four domains: (1) Clinical management with strict infection control, risk tools, and targeted drug therapies; (2) Patient education through competency-based training and mHealth tools, improving adherence by 42%; (3) Psychosocial support using telehealth and model of Managing Cancer And Living Meaningfully therapy, reducing distress by 38–45%; and (4) Interdisciplinary care with structured pathways lowering complications by 25–30%. Challenges include 40% non-adherence, rural care gaps, and inconsistent protocols. Future strategies include telemedicine (45% adherence gain), genetic risk tools, and machine learning for early detection.

## Linked entities

- **Diseases:** neutropenia (MONDO:0001475)

## Full-text entities

- **Diseases:** Neutropenia (MESH:D009503), infection (MESH:D007239), neutropenic (MESH:D044504), Cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12554692