# A Case of Spontaneous Atraumatic Renal Bleeding (Wunderlich Syndrome)

**Authors:** Lydia MY Chang, Shail Shah, Dora Moon

PMC · DOI: 10.7759/cureus.93311 · 2025-09-26

## TL;DR

A 72-year-old woman with atrial fibrillation experienced a rare spontaneous kidney bleed, which was successfully treated with embolization.

## Contribution

This case highlights the rare occurrence and effective management of Wunderlich Syndrome in a patient on anticoagulant therapy.

## Key findings

- The patient presented with symptoms of sudden left abdominal pain and dizziness due to a renal bleed.
- Imaging confirmed an active renal arterial bleed, leading to successful embolization of pseudoaneurysms.
- Conservative management failed, necessitating interventional treatment for ongoing bleeding.

## Abstract

We present an uncommon case of atraumatic spontaneous renal hemorrhage in a 72-year-old woman with a background of atrial fibrillation on edoxaban who presented with a sudden onset of left abdominal pain, nausea, vomiting, lethargy, and dizziness. Cross-sectional imaging was performed and confirmed an ongoing renal bleed. She had a trial of conservative management; however, repeated imaging showed an ongoing, slow but active renal arterial bleed; hence, she underwent an embolization procedure. On-table angiogram revealed pseudoaneurysms in the upper and lower poles of the kidney, for which she underwent successful renal artery embolization.

## Linked entities

- **Chemicals:** edoxaban (PubChem CID 10280735)
- **Diseases:** atrial fibrillation (MONDO:0004981)

## Full-text entities

- **Diseases:** vomiting (MESH:D014839), atrial fibrillation (MESH:D001281), abdominal pain (MESH:D015746), dizziness (MESH:D004244), nausea (MESH:D009325), Wunderlich Syndrome (MESH:D013577), pseudoaneurysms (MESH:D017541), bleed (MESH:D006470), Renal Bleeding (MESH:D006030), lethargy (MESH:D053609)
- **Chemicals:** edoxaban (MESH:C552171)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12554368/full.md

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Source: https://tomesphere.com/paper/PMC12554368