# Giant retroperitoneal lipoma in 62-year-old male: a rare benign tumor in an unusual location

**Authors:** Abdulrahman Mohammed Abdulrahman Abouh, Mohammedbabalrahma Bashier Ahmed Koko, Esra Altayeb Alhady Massry, Ahmed Idris Abdelrahman Idris, Al-Siddig Mohammed Abdulrahman Abouh, Ahmed Abdalla Agab Eldour

PMC · DOI: 10.1093/jscr/rjaf859 · 2025-10-26

## TL;DR

A rare case of a large benign lipoma in the retroperitoneal cavity of a 62-year-old man is reported, emphasizing the importance of histopathology for accurate diagnosis.

## Contribution

This case highlights the rarity and diagnostic challenges of retroperitoneal lipomas, emphasizing the need for histopathological confirmation.

## Key findings

- A 62-year-old male had a 15.5 × 12.3 × 22.8 cm retroperitoneal lipoma successfully excised.
- Histopathology confirmed the mass as a benign lipoma, not a liposarcoma.
- Complete surgical excision led to an excellent prognosis with no adverse events.

## Abstract

Lipomas occur elsewhere in the body; however, retroperitoneal lipomas are extremely rare, benign tumors. Unlike liposarcoma, it lacks malignant potential but may grow to a large size because of its spacious retroperitoneal cavity. We report a 62-year-old male presented with progressive abdominal distension for over 2 months. Imaging revealed a large retroperitoneal fatty mass (15.5 × 12.3 × 22.8 cm) herniating through the obturator and sciatic foramina, displacing pelvic organs. Laparotomy with complete excision was performed, and histopathology confirmed a benign lipoma. The patient was discharged without adverse events. Retroperitoneal lipomas are rare and often indistinguishable from liposarcomas on imaging. Histopathology remains crucial for diagnosis, and complete surgical excision provides excellent prognosis, as demonstrated in this case. Differential diagnosis of retroperitoneal masses should include retroperitoneal lipomas, although they are rare. Imaging is useful; however, histopathological examination is essential for definitive diagnosis.

## Linked entities

- **Diseases:** lipoma (MONDO:0005106), liposarcoma (MONDO:0003585)

## Full-text entities

- **Diseases:** abdominal distension (MESH:D000007), Lipomas (MESH:D008067), liposarcoma (MESH:D008080), fatty mass (MESH:C536030), benign tumors (MESH:D009369), Retroperitoneal lipomas (MESH:D012186)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12554160/full.md

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Source: https://tomesphere.com/paper/PMC12554160