# Perinatal Stroke and Cor Triatriatum Sinister: A Case Report

**Authors:** Inês Mazeda, Marisa Rodrigues, Jorge Moreira, Sandra Ramos

PMC · DOI: 10.7759/cureus.93211 · 2025-09-25

## TL;DR

A child with a history of perinatal stroke was found to have a rare heart defect, suggesting a possible link between subtle heart anomalies and fetal strokes.

## Contribution

This case report highlights a potential association between non-obstructive CTS and cryptogenic perinatal stroke.

## Key findings

- The child had a non-obstructive CTS identified after a perinatal stroke.
- Neuroimaging confirmed left-sided brain injury consistent with a past vascular event.
- Early multidisciplinary intervention led to a favorable neurodevelopmental outcome.

## Abstract

Cor triatriatum sinister (CTS) is a rare congenital heart defect characterized by a fibromuscular membrane dividing the left atrium. Though often asymptomatic in incomplete forms, CTS has been associated with thromboembolic events. We describe a case of a female child with a history of perinatal stroke presenting with right hemiparesis. Prenatal imaging suggested lateral ventricle asymmetry and localized hemorrhage. Postnatal development was mostly normal until gait abnormalities emerged at 18 months. Neuroimaging confirmed left-sided brain injury consistent with a past vascular insult. Cardiac evaluation revealed non-obstructive CTS with no signs of hemodynamic compromise. Although a direct causal relationship could not be confirmed, the identification of CTS in a cryptogenic perinatal stroke case raises the possibility that subtle atrial anomalies may contribute to fetal thromboembolic events. This case reinforces the importance of comprehensive cardiac evaluation in perinatal strokes and illustrates a favorable neurodevelopmental outcome with early multidisciplinary intervention.

## Linked entities

- **Diseases:** Cor triatriatum sinister (MONDO:0020430)

## Full-text entities

- **Diseases:** atrial anomalies (MESH:D000013), gait abnormalities (MESH:D020233), vascular insult (MESH:D057772), brain injury (MESH:D001930), Perinatal Stroke (MESH:D066087), thromboembolic events (MESH:D013923), strokes (MESH:D020521), hemiparesis (MESH:D010291), hemorrhage (MESH:D006470), CTS (MESH:D003310), congenital heart defect (MESH:D006330), lateral ventricle asymmetry (MESH:D005146)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12553508/full.md

---
Source: https://tomesphere.com/paper/PMC12553508