GeneDrive.jl: A decision tool to optimize biological vector control strategies under climate change
Váleri N. Vásquez, Erin A. Mordecai, David Anthoff
TL;DR
GeneDrive.jl is a new software tool that helps plan mosquito control strategies, considering climate change and local health goals.
Contribution
GeneDrive.jl is the first software to optimize biological vector control strategies under climate change and local constraints.
Findings
GeneDrive.jl enables customized vector population reduction strategies using genetic biocontrol.
The software supports scenario-based testing of control strategies within a single platform.
Case studies demonstrate its use for suppressing Aedes aegypti populations in dengue-endemic regions.
Abstract
This paper introduces GeneDrive.jl, the first software package to optimize operational planning for the biological control of mosquito disease vectors (access: https://github.com/vnvasquez/GeneDrive.jl). Mosquitoes are responsible for transmitting a significant percentage of the global infectious disease burden, a problem being exacerbated as climate change shifts the range and alters the abundance of these temperature-sensitive arthropods. The efficacy and cost of vector control varies according to species, region, and intervention type. Meanwhile, existing computational tools lack the ability to explicitly tailor interventions for local health objectives and resource limitations. GeneDrive.jl addresses this equity and efficiency gap, which is of particular concern for the tropical regions that both bear the highest mosquito-borne disease burden and are subject to disproportionate…
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Taxonomy
TopicsInsect symbiosis and bacterial influences · Mosquito-borne diseases and control · Insect behavior and control techniques