# Diagnostic accuracy of history taking, physical examination, and auxiliary examination for thumb osteoarthritis: a systematic review

**Authors:** Yisha He, Patrick Krastman, Sita M. A. Bierma-Zeinstra, Gerald Kraan, Nina M. Mathijssen, Jos Runhaar

PMC · DOI: 10.1080/07853890.2025.2524086 · Annals of Medicine · 2025-06-26

## TL;DR

This study reviews the accuracy of history, physical exams, and tests for diagnosing thumb osteoarthritis, finding that some physical tests are highly accurate.

## Contribution

The paper systematically evaluates the diagnostic accuracy of various methods for thumb osteoarthritis, highlighting specific physical tests with high accuracy.

## Key findings

- History taking showed low certainty with sensitivity 47% to 100% and accuracy 40% to 80%.
- Physical examination had moderate certainty, with some tests like the adduction test showing accuracy above 90%.
- Auxiliary examination had limited evidence but showed 76% accuracy in one study.

## Abstract

To conduct a systematic review to evaluate the diagnostic accuracy of history taking, physical examination, and auxiliary examination for thumb osteoarthritis (OA).

MEDLINE ALL, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science Core Collection, and CINAHL were searched up to October 2023. Studies focused on patients with hand or thumb pain suspected of thumb OA, considering any diagnostic methods as the index test, with any diagnostic assessment of thumb OA as the reference standard were included. Sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were extracted. QUADAS and GRADE were applied to assess the evidence.

Seven studies were included. History taking (two studies, 1096 participants) showed very low certainty of evidence;physical examination (five studies, 427 participants) revealed moderate certainty of evidence; auxiliary examinations (one study, 20 participants) indicated low certainty of evidence. History taking showed sensitivity of 47% to 100%, specificity of 40% to 63%, and accuracy of 40% to 80%. Physical examination demonstrated sensitivity of 2% to 100%, specificity of 75% to 100%, and accuracy of 47% to 98%. Auxiliary examination exhibited sensitivity of 72%, specificity of 86%, and accuracy of 76%. The adduction test, extension test, and metacarpal pressure-shear tests were reported to have accuracy above 90% based on two studies.

Based on few studies, the diagnostic accuracy of history taking and physical examination for thumb OA varied across studies, while knowledge about auxiliary examination was limited. The adduction test, extension test, and metacarpal pressure-shear test are recommended for thumb OA diagnosis.

## Full-text entities

- **Diseases:** OA (MESH:D010003), thumb pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

45 references — full list in the complete paper: https://tomesphere.com/paper/PMC12551402/full.md

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Source: https://tomesphere.com/paper/PMC12551402