# Enhancing cervical cancer diagnosis with ensemble learning and shark optimization algorithm: comparative study of CT and MRI in cervical cancer diagnosis

**Authors:** Eman Hussein Alshdaifat, Amer Mahmoud Sindiani, Salem Alhatamleh, Hamad Yahia Abu Mhanna, Rola Madain, Mohammad Amin, Majd Malkawi, Ameera Jaradat, Hanan Fawaz Akhdar, Hasan Gharaibeh, Fatimah Maashey, Latifah Alghulayqah

PMC · DOI: 10.3389/fonc.2025.1608386 · Frontiers in Oncology · 2025-10-10

## TL;DR

This paper introduces a new AI-based method combining vision models and optimization algorithms to improve cervical cancer diagnosis using CT and MRI scans.

## Contribution

A novel methodology combining LVM and InternImage with the Shark Optimization Algorithm is proposed for cervical cancer diagnosis.

## Key findings

- The proposed model achieved 98.49% accuracy in diagnosing CT images and 92.92% accuracy in MRI images.
- CT and MRI imaging can detect tumor extension into cervical stroma, influencing treatment approaches.

## Abstract

Cervical cancer, one of the most common female cancers, can be detected with computed tomography (CT) and magnetic resonance imaging (MRI). Computer-aided diagnosis (CAD) methods based on artificial intelligence have been widely explored to improve traditional screening methods for cervical cancer detection. This study aims to compare the accuracy of CT and MRI in diagnosing cervical cancer using a novel methodology that combines the Large Vision Model (LVM) and InternImage, which reduces the misclassification of cervical tumors, especially in benign and malignant cases. InternImage (based on InceptionV3) extracts pre-trained deep features, making it more sensitive to tumor-specific patterns. At the same time, LVM focuses on fine-grained spatial features, helping to classify early changes in cervical pathology. In the Shark Optimization Algorithm (SOA), the procedure dynamically selects the optimal weight parameter, avoiding overreliance on a single model. This application improves generalization across different CT and MRI datasets. The performance of the proposed model is evaluated on two new datasets, KAUH-CCTD and KAUH-CCMD, collected from King Abdullah University Hospital (KAUH) in Jordan. The proposed model classified images into three categories: benign, malignant, and normal. The proposed model achieved the best performance in diagnosing CT images, with an accuracy of 98.49%, while achieving an accuracy of 92.92% in diagnosing MRI images. CT imaging, especially MRI, can detect tumor extension into the cervical stroma, which could change treatment approaches. Additionally, imaging plays a crucial role in monitoring treatment and patient progress to detect early disease relapses.

## Linked entities

- **Diseases:** cervical cancer (MONDO:0002974)

## Full-text entities

- **Diseases:** Cervical cancer (MESH:D002583), cancers (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

12 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12550778/full.md

## References

52 references — full list in the complete paper: https://tomesphere.com/paper/PMC12550778/full.md

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Source: https://tomesphere.com/paper/PMC12550778