# Burkitt Lymphoma Presenting With Acute Kidney Injury and Facial Nerve Palsy: A Case Report With Literature Review

**Authors:** Gana Odeh, Fawwaz Yassin, Jalal Abuomar, Abdoh Abdallah

PMC · DOI: 10.1002/ccr3.71363 · Clinical Case Reports · 2025-10-24

## TL;DR

A 2-year-old boy with Burkitt lymphoma presented with rare symptoms of kidney failure and facial nerve palsy, highlighting the need for clinicians to consider unusual symptom combinations.

## Contribution

This case report adds to the literature by documenting the rare co-occurrence of acute kidney injury and facial nerve palsy in Burkitt lymphoma.

## Key findings

- The patient presented with acute kidney injury and bilateral nephromegaly.
- He later developed left-sided facial nerve palsy and was diagnosed with Burkitt lymphoma.
- Despite initial treatment success, the patient's condition worsened and led to death.

## Abstract

Burkitt lymphoma is an aggressive non‐Hodgkin lymphoma. While kidney infiltration is well documented, acute kidney injury is an unusual presentation. Facial nerve palsy is even rarer. Here, we report a case of a 2‐year‐old boy with both of these unusual findings. He presented with acute kidney injury and bilateral nephromegaly. Two days later, he developed left‐sided facial nerve palsy. Imaging showed enlarged cervical lymph nodes. Bone marrow biopsy confirmed Burkitt lymphoma. He was treated following the COG ANHL01P1 protocol, with initial significant clinical improvement. Despite this, his condition deteriorated due to septic shock, and the patient died. This case emphasizes that Burkitt lymphoma can present with unusual symptoms. Therefore, it is important that clinicians maintain a high index of suspicion in cases with unusual constellations of symptoms, such as acute kidney injury and facial nerve palsy.

## Linked entities

- **Diseases:** Burkitt lymphoma (MONDO:0007243), acute kidney injury (MONDO:0002492), facial nerve palsy (MONDO:0005665)

## Full-text entities

- **Diseases:** Burkitt Lymphoma (MESH:D002051), kidney infiltration (MESH:D007674), non-Hodgkin lymphoma (MESH:D008228), Acute Kidney Injury (MESH:D058186), Facial Nerve Palsy (MESH:D005155), septic shock (MESH:D012772)
- **Chemicals:** ANHL01P1 (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12550592/full.md

## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC12550592/full.md

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Source: https://tomesphere.com/paper/PMC12550592