# Post‐Tuberculosis Adrenal Crisis in a Young Boy: A Case Report

**Authors:** Aisha Haleem, Saad Ashraf, Daniya Tarique, Muhammad Zohair, Ajeet Singh, Biruk Demisse Ayalew

PMC · DOI: 10.1002/ccr3.71345 · Clinical Case Reports · 2025-10-24

## TL;DR

A young boy experienced an adrenal crisis years after tuberculosis, highlighting the need for early detection and treatment.

## Contribution

Highlights the long-term adrenal complications of tuberculosis in children and emphasizes the importance of early diagnosis.

## Key findings

- Adrenal crisis can occur years after tuberculosis treatment in children.
- Early recognition and glucocorticoid replacement are critical for survival.
- Routine screening in high-risk patients may prevent fatal outcomes.

## Abstract

An adrenal crisis should be considered in children with a history of tuberculosis who present with shock, hypoglycemia, and hyperpigmentation. Even years after successful treatment, TB can cause irreversible adrenal damage leading to primary adrenal insufficiency. Early recognition and prompt glucocorticoid replacement are lifesaving. Routine screening in high‐risk patients may prevent delayed diagnosis and fatal outcomes.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076), adrenal crisis (MONDO:0019801), primary adrenal insufficiency (MONDO:0015128)

## Full-text entities

- **Diseases:** hyperpigmentation (MESH:D017495), Tuberculosis (MESH:D014376), Post (MESH:D000094025), Adrenal Crisis (MESH:D000310), hypoglycemia (MESH:D007003), shock (MESH:D012769), adrenal damage (MESH:D000307), TB (MESH:D014390), adrenal insufficiency (MESH:D000309)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12550515/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12550515/full.md

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Source: https://tomesphere.com/paper/PMC12550515